Not Yet RecruitingNot Applicable

Fibrinogen-to-Albumin Ratio as a Predictor of Acute Respiratory Distress Syndrome in Traumatic Brain Injury

Egypt350 participantsStarted 2026-07-01

Plain-language summary

this study aims to assess the ability of fibrinogen-to-albumin ratio to predict the development of Acute respiratory distress syndrome in traumatic brain injury patients.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients ≥ 18 years admitted to the ICU with traumatic Brain Injury * Admission to the ICU within 24 hours of injury. * Patients will be expected to remain under hospital care for follow-up * Availability of fibrinogen and albumin measurements within the first 24 hours of ICU admission. * Informed consent will be obtained from a legally authorized representative. Exclusion Criteria: * Preexisting advanced chronic liver disease, nephrotic syndrome, or protein-losing enteropathy. * Pre-existing ARDS on admission. * Recipient of albumin, fibrinogen concentrate, or cryoprecipitate before admission sampling. * Use of anticoagulant or fibrinolytic therapy before admission. * Active malignancy or severe systemic infection at admission. * Direct sever lung injury * Pregnancy * Refusal of consent

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

The accuracy of early fibrinogen-to-albumin ratio (within 24 hours of ICU admission) to predict the development of acute respiratory distress syndrome in traumatic brain injury patients.

Timeframe: up to 7 days after traumatic brain injury.

Trial details

NCT IDNCT07664358

SponsorTanta University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-12-01

Contact for this trial

Eman M Taher, MD

01090822808 emantaher6669@gmail.com

View on ClinicalTrials.gov More Fibrinogen Albumin Ratio trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.