Effect of Central Sensitization on Response to Physical Therapy in Patients With Partial Supraspi… (NCT07664137) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Effect of Central Sensitization on Response to Physical Therapy in Patients With Partial Supraspinatus Tear
60 participantsStarted 2026-06-30
Plain-language summary
This prospective observational study aims to investigate whether central sensitization influences the response to physical therapy in patients with partial supraspinatus tendon tears. Participants will undergo standardized clinical evaluation before treatment and after a 6-week physical therapy program. Pain intensity, shoulder function, disability, and central sensitization-related symptoms will be assessed using validated outcome measures. The study seeks to determine the relationship between baseline central sensitization status and treatment outcomes, thereby identifying factors that may predict rehabilitation success and support individualized treatment strategies for patients with partial supraspinatus tears.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Adults aged 18 to 65 years. Diagnosis of supraspinatus partial-thickness tear confirmed by clinical examination and magnetic resonance imaging (MRI).
Presence of shoulder pain for at least 6 weeks. Candidates for a standardized physical therapy and rehabilitation program. Ability to understand the study procedures and provide written informed consent.
Exclusion Criteria:
Full-thickness rotator cuff tear or history of previous shoulder surgery on the affected side.
Acute fracture, shoulder dislocation, or other major traumatic injury involving the affected shoulder.
Inflammatory rheumatic diseases, active infection, or malignancy affecting the musculoskeletal system.
Neurological disorders that may influence pain perception or upper extremity function (e.g., stroke, cervical myelopathy, peripheral neuropathy).
Severe glenohumeral or acromioclavicular osteoarthritis requiring surgical treatment.
Receipt of corticosteroid injection or any invasive shoulder intervention within the previous 3 months.
Participation in another structured rehabilitation program for the affected shoulder within the previous 3 months.
Pregnancy or inability to comply with the study protocol or complete the required questionnaires.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Shoulder Pain and Disability Index (SPADI) Total Score
Timeframe: Baseline, Week 3, and Week 6
Trial details
NCT IDNCT07664137
SponsorKanuni Sultan Suleyman Training and Research Hospital