CompletedNot Applicable

Effects of EPA Supplementation on Patients With Unresectable Hepatocellular Carcinoma.

Spain18 participantsStarted 2019-03-04

Plain-language summary

Dietary intervention with eicosapentaenoic acid combined with chemotherapy may shift inflammatory mediators toward resolution in non-resectable hepatocarcinoma and help to preserve muscle mass.

Who can participate

Age range

18 Years – 75 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Participants diagnosed with unresectable HCC, candidates for systemic treatment with Sorafenib or similar agents. * Eastern Cooperative Oncology Group (ECOG) performance status of 0-1. * Life expectancy \> 8 weeks. * Not eligible for curative treatment (surgical resection/ablative therapy/liver transplantation). * Not having a history of previous or concomitant malignancy except when a disease-free interval \> 5 years had been documented. * Not receiving any other systemic antitumor agents (docetaxel, doxorubicin, irinotecan). Exclusion Criteria: * Allergy to omega-3 acid or fish-derived products. * Psychological or medical conditions that can interfere with study participation or the ability to provide informed consent. * Drug abuse (except for alcohol). * Any experimental therapy within 30 days prior to study entry. * Recurrent epistaxis

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Effect of EPA supplementation on muscle mass

Timeframe: At baseline, and at 12 weeks (study completion)

Trial details

NCT IDNCT07664007

SponsorInstituto de Investigación Sanitaria Aragón

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-09-17

View on ClinicalTrials.gov More Hepatocellular Carcinoma trials

Who can participate

Age range

18 Years – 75 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.