Not Yet RecruitingPhase 3

Intravenous Lidocaine to Prevent Post-Fundal Pressure Headache During Cesarean Section

Egypt680 participantsStarted 2026-07-01

Plain-language summary

This prospective randomized controlled multicenter study will be conducted to evaluate the effects of pre-emptive IV lidocaine dose on the incidence and severity of intraoperative headache that may occur after the extra-abdominal manual uterine fundal pressure in patients undergoing cesarean section under spinal anesthesia.

Who can participate

Age range

18 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Aged ≥ 18 years * American Society of Anesthesiologists (ASA) Physical Status II * Scheduled for elective cesarean section under spinal anesthesia Exclusion Criteria: * Patients declined to participate in the trial, * Patients with history of any type of headache, mental illness, or cerebrovascular diseases * Previous epidural insertion for painless labor or any other indications; * Patients on opioid or analgesic medications; * Those with pregnancy-induced hypertension or diabetic patients, * Allergy to lidocaine; * Contraindication or failure of spinal anesthesia.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Incidence of intraoperative headache

Timeframe: Up to the end of surgery.

Trial details

NCT IDNCT07661758

SponsorTanta University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-11-01

Contact for this trial

Osama M Rehab, MD

+201095210806 osamarehab@med.tanta.edu.eg

View on ClinicalTrials.gov More Intravenous Lidocaine trials