High-Intensity Laser Therapy (HILT) in Patients With Knee Osteoarthritis (NCT07661407) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
High-Intensity Laser Therapy (HILT) in Patients With Knee Osteoarthritis
72 participantsStarted 2026-07-03
Plain-language summary
This randomized placebo-controlled trial aims to evaluate the effectiveness of High-Intensity Laser Therapy (HILT) as an adjunct to standard outpatient physiotherapy in patients with knee osteoarthritis. Seventy-two participants will be randomly assigned to receive either conventional physiotherapy combined with active HILT or conventional physiotherapy combined with sham HILT. Outcomes related to pain, knee function, physical performance, muscle strength, range of motion, psychosocial factors, quality of life and body composition will be assessed at baseline, after the intervention, and at 8-week follow-up.
Who can participate
Age range
40 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Radiographically confirmed knee osteoarthritis
* Mild-to-moderate disease severity
* Pain ≥4 on VAS for at least 3 months
* Ability to participate in physiotherapy
* Informed consent
Exclusion Criteria:
* Advanced OA requiring surgery
* Previous knee arthroplasty
* Knee instability
* Acute inflammation
* Neurological disorders affecting gait
* Neuropathies or myopathies
* Active inflammatory arthritis
* Recent lower-limb injury (\<6 months)
* Intra-articular injections within 3 months
* Cancer, pregnancy, epilepsy
* Electronic implants or pacemaker
* Active local infection
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in KOOS Pain Subscale Score
Timeframe: Baseline, immediately after the 2-week intervention, and 8 weeks after completion of treatment.