Epidemiological Cluster Evaluation in Patients Admitted to Internal Medicine, With at Least One o… (NCT07660757) | Clinical Trial Compass
CompletedNot Applicable
Epidemiological Cluster Evaluation in Patients Admitted to Internal Medicine, With at Least One of the Following Diagnoses: Heart Failure, COPD, Renal Failure. The FADOI IN-CluDiMI Study
Italy4,500 participantsStarted 2023-01-02
Plain-language summary
Improved medical care has led to an increase in both the age and clinical complexity of patients admitted to Internal Medicine wards, characterized by multiple chronic diseases. Multimorbidity is a common issue in the elderly, significantly associated with higher mortality, functional decline, and poorer quality of life. The concept of "disease clustering" goes beyond simple multimorbidity or comorbidity by grouping statistically associated morbid conditions to understand their interconnections, shared risk factors, and pathophysiological mechanisms. The goal is to identify these clusters in relation to the most common chronic conditions in Internal Medicine: heart failure, chronic obstructive pulmonary disease (COPD), and chronic kidney disease.This is an observational, multicenter, prospective, national study sponsored by the FADOI Foundation (Federation of Associations of Internal Medicine Hospital) and this is a non-profit research project. It aims to involve about 50 Internal Medicine Units, targeting the enrollment of approximately 100 consecutive adult patients per unit, for a total of at least 1500 subjects per pathology group.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients admitted to Internal Medicine with a diagnosis of at least one of the following chronic conditions:
* heart failure
* COPD
* chronic kidney disease
* Acceptance of participation in the study by signing the informed consent
Exclusion Criteria:
* Patients who do not consent to participate in the study
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This study was looking at patients who have combinations of heart failure, COPD, and chronic kidney disease together — do I have more than one of these conditions, and if so, how does that affect my overall treatment plan?
2Since this study focused on identifying disease 'clusters' — meaning how these three conditions overlap and interact — what did research like this find that might be relevant to how my own combination of conditions is managed?
3This trial is completed but was observational, meaning it collected data rather than testing a new treatment — are there any findings or follow-up studies from research like this that my care team is already using to guide decisions for patients like me?
4Because this study enrolled patients admitted to internal medicine wards with these chronic conditions, does my current health situation suggest I'm at a stage where my conditions are interacting in ways that need closer or more coordinated monitoring?
5Are there any active treatment trials or next steps that came out of research like this one that might be worth exploring, or is standard care currently the better path for managing my specific combination of conditions?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Identifying disease clusters (defined as the co-presence of at least two additional diseases) in patients suffering from at least one of the following chronic diseases: heart failure, COPD, and chronic kidney disease