CompletedNot Applicable

Proprioceptive Training With or Without Strength Training on Tibialis Anterior in Chronic Stroke Patients

Pakistan76 participantsStarted 2025-09-22

Plain-language summary

This randomized controlled trial aims to investigate the effects of proprioceptive training with and without tibialis anterior strength training in individuals with chronic stroke. Chronic stroke survivors commonly experience impaired balance, gait disturbances, reduced lower-limb muscle strength, and functional limitations that affect mobility and independence. The tibialis anterior muscle plays an important role in ankle dorsiflexion, foot clearance during walking, and postural stability. Participants with chronic stroke will be randomly assigned to one of two intervention groups. One group will receive proprioceptive training combined with tibialis anterior strength training, while the other group will receive proprioceptive training alone. Interventions will be administered over a six-week period. Outcomes related to muscle strength, balance, gait performance, and functional mobility will be assessed at baseline and during follow-up assessments. The study seeks to evaluate rehabilitation approaches targeting lower-limb motor and sensory impairments in individuals with chronic stroke and to contribute evidence regarding interventions designed to improve functional recovery and mobility.

Who can participate

Age range

45 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Residual paresis in the lower extremity (Shahid et al., 2013). * Ability to sit unsupported for 30 seconds (Shahid et al., 2013). * Ability to follow 3 steps command (Shahid et al., 2013). * Least degree of the associated reaction (Shahid et al., 2013). * Survivor with stable C.V.S system (Shahid et al., 2013). * Survivor without fixed contracture of the lower extremity (Shahid et al., 2013). * Participants having a history of stroke within the prior 6 months or more (S. H. Chae et al., 2017). * Participants having ability to understand the directions from the researchers (those with a MMSE score of 24 or greater) (S. H. Chae et al., 2017). * Patients with grade 1 on modified Ashworth scale (Jan et al., 2019). Exclusion Criteria: * Presence of acute musculoskeletal symptoms (S. H. Chae et al., 2017). * Participants having inability to communicate, and those deemed unable to participate in the study by the researchers (S. H. Chae et al., 2017). * Serious cardiac condition (history of the CHF, documented serious and unstable cardiac arrhythmias (Shahid et al., 2013). * Hypertrophic cardiomyppathy, severe aortic stenosis, history of severe COPD. * Angina and dyspnea at rest or during ADL (Shahid et al., 2013).

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Muscle Strength of Tibialis Anterior

Timeframe: Baseline, Week 3, and Week 6

Trial details

NCT IDNCT07659522

SponsorUniversity of Lahore

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-06-14

View on ClinicalTrials.gov More Stroke trials