RecruitingNot Applicable

MCG for Non-Obstructive Myocardial Ischemia

China3,786 participantsStarted 2025-04-15

Plain-language summary

The aim of this prospective study is to identify Non-Obstructive Myocardial Ischemia of patients who have acute chest pain using Magnetocardiography.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 18 years or older; * Patients with symptoms of myocardial ischemia such as angina pectoris, who have CAG showing \<70% stenosis at the most severe site or CTA showing non-severe stenosis * Signed informed consent. Exclusion Criteria: * Patients with absolute or relative contraindications to CFR-loaded myocardial perfusion, including acute myocardial infarction within 48 hours, significant left main coronary artery stenosis, bronchial asthma, and adenosine injection allergy; * Patients with Non-ischemic dilated cardiomyopathy, or hypertrophic cardiomyopathy, or moderate or severe valvular disease; * Patients with Hemodynamic instability (systolic blood pressure\<90 mmHg, or who requires vasoactive drugs), or patients with tachyarrhythmia, #degree atrioventricular block and above that have not returned to normal; * Patients who have severe renal abnormality with eGFR \<30 ml/min, or patients who are on dialysis; * Patients with malignant tumors with predicted survival of less than 1 year; * Pregnant or breastfeeding women; * Patients who are unable to enter the MCG device, who are unable to perform MCG examination due to interference from metal implants or other reasons, or who are deemed by the investigators to be unsuitable for enrollment.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1This trial is testing whether MCG — magnetocardiography — can accurately detect non-obstructive myocardial ischemia, so would participating mainly help researchers gather data, or could the results directly affect my own diagnosis and care?
2Since this study is listed as Phase NA, which often means it's a diagnostic or device evaluation rather than a treatment trial, can you explain what MCG actually involves for me as a patient, and whether it carries any risks compared to the imaging or tests I might already be having?
3Non-obstructive myocardial ischemia can be tricky to detect with standard tests — how does MCG compare to what you would normally use to diagnose my condition, and is there a chance joining this study delays or changes the diagnostic workup you'd otherwise recommend?
4If the MCG test in this study doesn't clearly detect ischemia in my case, would I still receive a full standard diagnostic evaluation, or could a negative result leave questions about my heart health unanswered?
5Are there any other established diagnostic pathways or clinical options for non-obstructive myocardial ischemia that I should consider alongside or instead of enrolling in this study?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Efficacy of MCG for the detection of Non-Obstructive Myocardial Ischemia

Timeframe: from the date of enrollment until the date of discharge, up to 30 days]

Trial details

NCT IDNCT07657546

SponsorQilu Hospital of Shandong University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-06-30

Contact for this trial

Jiaojiao Pang, Doctor

0086-0531-82165398 jiaojiaopang@126.com

View on ClinicalTrials.gov More Myocardial Ischemia trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.