Oral Versus Intravenous Magnesium on Emergence Delirium (NCT07655817) | Clinical Trial Compass
Not Yet RecruitingPhase 2/3
Oral Versus Intravenous Magnesium on Emergence Delirium
Egypt360 participantsStarted 2026-06-24
Plain-language summary
This prospective randomized controlled study will be conducted to compare the effects of preoperative oral magnesium and intraoperative IV magnesium on the incidence and severity of emergence delirium in children undergoing adenotonsillectomy using sevoflurane anesthesia.
Who can participate
Age range
4 Years – 7 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Children aged 4 to 7 years
* American Society of Anesthesiologist (ASA) Status I or II
* Planned for an adenotonsillectomy procedure under sevoflurane general anesthesia.
Exclusion Criteria:
* Parents declined to participate in the trial
* Behavioral changes, neurological or psychiatric problems
* Anticonvulsant or sedative drugs
* Physical or developmental abnormalities
* Allergies to magnesium
* cardiovascular, renal, bone, or gastrointestinal diseases.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Since this trial is comparing oral versus intravenous magnesium specifically in children having adenotonsillectomy, can you explain whether my child would likely receive one form or the other, and what the difference in experience might be for them?
2This study is still not yet recruiting — what does that mean for our timeline, and is there a standard approach your team already uses to manage emergence delirium after adenotonsillectomy that we could pursue in the meantime?
3Because this is a Phase 2/Phase 3 trial, what is already known about the safety of giving magnesium to children in a surgical setting, and are there any risks specific to my child's age, weight, or health history that I should be aware of?
4The trial is measuring how often emergence delirium happens after surgery — can you help me understand how distressing emergence delirium typically is for children and parents, and how significant a reduction would need to be to make participation worthwhile for us?
5Are there non-experimental options already available at your hospital to reduce the chance of emergence delirium after adenotonsillectomy, and how would those compare to what this trial is testing?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.