Wound Healing, Dressing Type, and Dressing Change Frequency in THA (NCT07655388) | Clinical Trial Compass
RecruitingNot Applicable
Wound Healing, Dressing Type, and Dressing Change Frequency in THA
Serbia90 participantsStarted 2026-05-25
Plain-language summary
Surgical wound complications following primary total hip arthroplasty remain a significant clinical challenge despite advances in wound care technologies. The optimal choice of dressing and frequency of dressing changes remain insufficiently investigated, particularly regarding their influence on wound healing and the wound microenvironment.
This prospective, randomized, controlled clinical trial aims to evaluate the impact of dressing type and dressing change frequency on surgical wound healing in patients undergoing primary total hip arthroplasty. Ninety patients will be allocated into three treatment groups receiving either a capillary-action dressing system (VACUTEX™) or standard dressings with different dressing change intervals.
The study will assess time to complete wound epithelialization, postoperative wound complications, pain intensity, wound temperature, exudate pH, length of hospital stay, and time to suture removal. In addition, the study will investigate the potential role of wound temperature and exudate pH as early indicators of impaired healing and postoperative complications.
Who can participate
Age range
65 Years – 95 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Patients scheduled for primary total hip arthroplasty (THA) Age ≥ 65 years Ability to provide informed consent Patients with closed surgical incision suitable for standard postoperative wound care
Exclusion Criteria:
Revision hip arthroplasty Active infection at the time of surgery Immunosuppressive therapy or severe immunodeficiency Known allergy to dressing materials used in the study Severe peripheral vascular disease affecting wound healing Inability to comply with follow-up protocol
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is comparing different types of wound dressings and how often they're changed after total hip replacement — do you think the specific dressing approach used in this study would fit well with how you normally manage my wound care after surgery?
2Since this trial is measuring how long it takes for the wound to fully close after hip replacement, what does that mean for my recovery timeline, and how does it compare to what I'd expect with your standard wound care routine?
3The trial doesn't have a traditional phase like drug studies do — can you help me understand what that means for what's already known about the safety and effectiveness of the dressing types being tested?
4If I join this study, how often would I need to come in for wound checks or dressing changes, and is that realistic given my schedule and distance from the clinic?
5Before considering this trial, is there a standard wound dressing approach you'd normally use after my hip replacement that I should understand first, so I can compare it to what the study is testing?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Time to complete wound epithelialization
Timeframe: Postoperative day 30 (90 or more in case of wound complications according to CDC criteria)