SPSIP Versus RISS Block in Volume-Preserving VATS (NCT07655336) | Clinical Trial Compass
RecruitingNot Applicable
SPSIP Versus RISS Block in Volume-Preserving VATS
Turkey (Türkiye)84 participantsStarted 2026-06-18
Plain-language summary
This prospective randomized controlled study aims to compare the effects of Serratus Posterior Superior Intercostal Plane (SPSIP) block and Rhomboid Intercostal and Subserratus (RISS) block on postoperative pain, respiratory function, and recovery quality in patients undergoing volume-preserving video-assisted thoracoscopic surgery (VATS). Eighty-four patients will be randomized in a 1:1 ratio to receive either SPSIP block or RISS block. The primary outcome is the incidence of somatic pain at the chest drain insertion site at postoperative 2 hours. Secondary outcomes include pain scores, opioid consumption, quality of recovery, diaphragmatic function, pulmonary function, rescue analgesic requirements, postoperative nausea and vomiting, and block-related complications.
Who can participate
Age range
18 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients scheduled for elective biportal video-assisted thoracoscopic surgery (VATS) with lung parenchyma-preserving thoracic procedures under general anesthesia
* American Society of Anesthesiologists (ASA) physical status I-III
* Age between 18 and 75 years
* Provision of written informed consent
Exclusion Criteria:
* Use of anticoagulant or antiplatelet therapy
* Bleeding diathesis
* Known allergy to local anesthetics
* Infection at the planned block site
* Severe chronic pulmonary disease or advanced respiratory failure (e.g., severe COPD or restrictive lung disease)
* Cognitive impairment preventing reliable NRS assessment
* Pregnancy or lactation
* Chronic opioid use (regular use for ≥3 months)
* Severe hepatic or renal failure
* Refusal to participate
* Technical failure or unsuccessful regional block
* Conversion to open thoracotomy during surgery
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is comparing two different nerve block techniques — SPSIP and RISS — for pain control after chest surgery, so can you explain what each of these blocks involves and which one you currently use in your practice?
2Since this trial is specifically measuring pain at the chest tube insertion site, how significant is that type of pain typically after VATS surgery, and how does it compare to other sources of discomfort I might experience during recovery?
3The trial is listed as 'not yet recruiting,' so do you know when it might open and whether waiting for it could affect my treatment timeline or overall outcome?
4Because this is a Phase NA study comparing two existing regional anesthesia techniques rather than testing a new drug, what does that mean for what's already known about the safety of both approaches?
5If I don't end up being part of this trial, what pain management approach would you use for my VATS procedure, and would it be one of the two blocks being studied here?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Incidence of Somatic Pain at Chest Tube Insertion Site