Investigating the Analgesic Efficacy and Ease of Perfomance of Modified Throracoabdominal Plane B… (NCT07654556) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Investigating the Analgesic Efficacy and Ease of Perfomance of Modified Throracoabdominal Plane Block and Comparing it With Erector Spinea Plane Block in Laparacopic Sleeve Gasterctomy Surgeries
64 participantsStarted 2026-07-01
Plain-language summary
Interest in surgical weight loss interventions continues to rise in the face of what has been dubbed the obesity epidemic. The most popular of these weight loss interventions is laparoscopic sleeve gastrectomy, which has proven to reduce morbidity and mortality of morbidly obese patients. The aim of effective perioperative pain management extends beyond increased patient comfort and includes reduced recumbency period, enhanced recovery, reduced hospital stay, and lowers postoperative complication rates.
Effective postoperative pain management has traditionally relied on multimodal strategies that combine systemic opioids, non-opioid medications, and regional anesthesia. Despite their efficacy, opioids are associated with a range of undesirable effects, such as nausea, vomiting, sedation, pruritus, and respiratory depression, which may impede early mobilization and recovery. These concerns have accelerated the adoption of ultrasound-guided regional anesthesia techniques as part of Enhanced Recovery After Surgery (ERAS) protocols, delivering superior pain control with fewer systemic adverse effects.
Who can participate
Age range
18 Years – 60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients from both sexes.
* 18 to 60 years old.
* ASA physical status II-III scheduled for laparoscopic sleeve gastrectomy.
* Patients with BMI (40-50) kg/ m2
Exclusion Criteria:
* Patient Refusal
* Lack of patient cooperation.
* Patients with any contraindication to regional nerve blocks as coagulopathy or infection at site of injection
* Patients with anatomical abnormalities at site of injection
* Patients with known hypersensitivity to bupivacaine, or any of the used drugs.
* Patients with pre-existing neurological disorder
* Patients with chronic pain syndromes including fibromyalgia, complex regional pain syndrome (CRPS), or chronic pain requiring long-term opioid or neuropathic pain medications.
* Patients with history of long-acting opioids, steroids, anticonvulsants perioperatively.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial compares two nerve block techniques — a modified thoracoabdominal plane block and an erector spinae plane block — for pain control after laparoscopic sleeve gastrectomy; which of these, if either, does my surgical team already use, and how does that affect whether this trial might be relevant to my care?
2Since this trial is listed as 'not yet recruiting,' how long might it be before it actually opens, and would waiting to potentially participate delay my surgery in a way that affects my health?
3The trial has no assigned phase, which suggests it's more of a procedural comparison than a drug study — can you help me understand what that means for what is and isn't yet known about the safety and effectiveness of these two block techniques?
4The main thing being measured is postoperative pain using a Visual Analogue Score — can you explain how well-controlled pain after sleeve gastrectomy typically is with current standard approaches, and whether joining a study like this would change what pain management I'd otherwise receive?
5If I don't participate in this trial, what pain control methods would you recommend for my laparoscopic sleeve gastrectomy, and are either of these two nerve block techniques already available to me outside of the study?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.