A Clinical Study of TQB2930 Injection and Chemotherapy With or Without Bevacizumab in the Treatment of Advanced Colorectal Cancer

Inclusion Criteria: * Subjects voluntarily participate in this study, sign the informed consent form, and have good compliance * Age: 18-75 years (including the boundary when signing the informed consent form) * Eastern Cooperative Oncology Group (ECOG) score: 0-1 * Expected survival of more than 3 months * Unresectable locally advanced or metastatic colorectal cancer diagnosed by histopathology/cytology * HER2 positive tested * Presence of at least one measurable disease according to Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 criteria * Subjects should agree to use contraception during the study and for 6 months after the end Exclusion Criteria: * Patients with previously confirmed Microsatellite Instability Microsatellite Instability-High Deficient Mismatch Repair (MSI-H/dMMR) * Presence of conditions affecting intravenous, venous blood sampling, or multiple factors affecting oral medications * Active inflammatory bowel disease within 28 days prior to first dose * Other malignancies within 5 years prior to the first dose or currently suffering from other malignancies * Unresolved toxicity greater than CTCAE Grade 1 due to any prior therapy * Major surgical treatment, significant traumatic injury within 28 days prior to the first dose or anticipation of major surgery during study treatment * Had wounds or fractures that had not been healed for a long time * Cerebrovascular accident, deep venous thrombosis and pulmonary embolism within 6 months prior to the …