Infant RSV Immunity Study (NCT07653347) | Clinical Trial Compass
RecruitingNot Applicable
Infant RSV Immunity Study
Canada300 participantsStarted 2026-01-15
Plain-language summary
Respiratory Syncytial Virus (RSV) is a main global cause of respiratory illness and death in infants. Previous infant vaccine trials have failed to demonstrate protection. Moreover, RSV infection during early infancy, particularly in infants younger than 4 months of age, is associated with more severe disease, reduced immune protection, and an increased risk of developing childhood asthma. This study aim to investigate the immunological and long-term health effects of a first exposure to RSV early (\<4 months) versus late (\>6-9 months) in infancy.
Who can participate
Age range
6 Months
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Birthing parent/child pairs with a delivery date in April, May or June or September, October or November who delivered or are planning to deliver at BC Women's Hospital + Health Centre or a nearby, local hospital.
Exclusion Criteria:
Severe pregnancy-related complications or chronic medical conditions in the children making them automatically eligible to receiving RSV immunoprophylaxis in British Columbia (e.g. infants born prematurely \< 35 weeks of gestation, or with chronic medical conditions).
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This study is measuring both RSV antibody response and childhood asthma symptoms in infants — can you help me understand whether there's a known connection between RSV infection and my child's risk of developing asthma, and why that makes this study relevant to us?
2Since this trial is listed as 'Phase NA,' it doesn't fit the usual Phase 1, 2, or 3 framework — can you tell me what type of study this actually is, whether it's observational or involves any interventions, and what that means for my baby's safety and what we'd be committing to?
3The study is actively recruiting right now — what would participation actually look like day-to-day for my infant and me, including how many visits, what samples or measurements are taken, and how long we'd be involved?
4Given that this trial is measuring RSV antibody levels, would my child's current vaccination history or any prior RSV exposure affect whether this study would even be informative for them?
5Are there standard preventive options for RSV in infants, like monoclonal antibodies, that I should be considering first, and how would you weigh those against enrolling in this study?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
RSV antibody response
Timeframe: Post-respiratory season 2027 (May 2027)