HF-rTMS Primed Balance Training on Corticomotor Excitability, Balance, and Gait in Parkinson's (NCT07653256) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
HF-rTMS Primed Balance Training on Corticomotor Excitability, Balance, and Gait in Parkinson's
20 participantsStarted 2026-07-01
Plain-language summary
This study aims to investigate the effects of repeated transcranial magnetic stimulation combined with modified otago exercise program balance training intervention on motor cortex excitability, balance, and gait performance in patients with Parkinson's disease.
Who can participate
Age range
40 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Diagnosed with idiopathic PD
* Aged between 40-80 years
* Stable on antiparkinsonian medication ( \> 3 months)
* H\&Y I-III
* Able to walk continuously for at least 10 minutes
* The ability to follow commands and instructions
Exclusion Criteria:
* Neurological diseases other than PD
* Severe musculoskeletal, cardiopulmonary disorders
* MMSE \< 24
* Contraindications for TMS
* Have undergone or are scheduled to undergo neurological surgery during the study participation period
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial combines high-frequency repetitive TMS with balance training — can you explain what each of those two parts actually involves during a session, and whether that combination is something my current health and Parkinson's symptoms could handle?
2The trial is listed as 'not yet recruiting,' so if I'm interested, how long might it realistically be before it opens, and what should I be doing in the meantime to manage my balance and gait symptoms?
3The study is measuring things like cortical silent period and intracortical inhibition, which are signals of how well my motor cortex is working — is there anything in my current condition that would make those measurements less useful or harder to interpret for me specifically?
4Since this is listed as Phase NA, which often means it's an early feasibility or mechanistic study, what does that mean for how much is already known about whether this combination approach is safe and beneficial for someone at my stage of Parkinson's?
5The trial tracks balance using the Mini-BESTest and fall confidence using the FES-I scale — given where I currently stand on those measures, would standard physical or occupational therapy be a better first step before considering an experimental protocol like this?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Corticospinal inhibition : Cortical silent period (CSP) (ms)