EMBRACE-OBS: Single-Site Observational Registry of Patient-Reported Outcomes Following MMA Emboli… (NCT07652034) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
EMBRACE-OBS: Single-Site Observational Registry of Patient-Reported Outcomes Following MMA Embolization for Migraine
United States50 participantsStarted 2026-07-01
Plain-language summary
EMBRACE-OBS is the first phase of the EMBRACE research program. This single-site observational registry accesses and analyzes patient-reported outcome data already collected through routine clinical care from adults with migraine who have undergone or plan to undergo middle meningeal artery (MMA) embolization. The study describes changes in headache frequency, headache severity, medication use, migraine-related disability, quality of life, and reported adverse events over time without influencing clinical care.
Who can participate
Age range
18 Years – 64 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults aged 18 to 64 years
* Diagnosis of migraine
* Have undergone or plan to undergo middle meningeal artery (MMA) embolization as part of routine clinical care, independent of study participation
* Able and willing to provide informed consent
* Able to read and understand English sufficiently to complete informed consent and patient-reported outcome assessments
Exclusion Criteria:
* Age under 18 years
* Pregnancy at the time of enrollment
* Inability to provide informed consent
* Inability to read and understand English sufficiently to complete informed consent and patient-reported outcome assessments
* Insufficient clinical or patient-reported outcome data for the planned analyses
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is listed as 'not yet recruiting' — do you know when it's expected to open, and would it make sense for me to get evaluated now so I'm ready if I become eligible?
2Since this is an observational registry rather than a randomized controlled trial, does that mean everyone enrolled will have already decided to undergo MMA embolization, and I'd mainly be contributing data rather than being assigned to a new treatment?
3The primary outcome being tracked is change in headache frequency — based on my current migraine pattern, would my situation give meaningful data to this kind of study, and is headache frequency the most important measure of improvement for someone like me?
4MMA embolization is a procedure involving blood vessels in the head — what are the potential risks I should understand before even considering whether to pursue this treatment, with or without this registry?
5Are there standard or proven treatments I haven't yet tried that you'd recommend exploring before looking into something like MMA embolization, which may have less long-term safety data than established migraine therapies?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.