Financial Toxicity, Quality of Life, and Psychological Resources in Breast Cancer Survivors : A L… (NCT07651267) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Financial Toxicity, Quality of Life, and Psychological Resources in Breast Cancer Survivors : A Longitudinal Study
160 participantsStarted 2026-07-15
Plain-language summary
Breast cancer survivors face significant financial stress (also called financial toxicity) due to the high costs of cancer treatment. This financial stress can worsen quality of life. Previous studies have demonstrated that breast cancer survivors may draw on inner psychological strengths to cope effectively. This study aims to examine whether psychological resources, specifically resilience and posttraumatic growth (PTG), buffer the longitudinal association between financial toxicity and quality of life (QoL) among breast cancer survivors.
Hypotheses: H1: Financial toxicity is negatively associated with QoL over time. H2: Resilience moderates the association between financial toxicity and QoL, such that higher resilience attenuates the negative impact of financial toxicity.
H3: Posttraumatic growth (PTG) moderates the association between financial toxicity and QoL, such that moderate to high levels of PTG attenuate the negative impact of financial toxicity.
Participants will complete questionnaires at three time points: before their first chemotherapy cycle, at two months (mid-treatment), and at four months (end of chemotherapy). The questionnaires measure financial stress, quality of life, resilience, and posttraumatic growth.
The study plans to enroll at least 160 participants. Data will be analyzed using statistical methods that track changes across time and test whether resilience and posttraumatic growth buffer the impact of financial stress on quality of life. All data will be de-identified and stored securely.
Who can participate
Age range
18 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Histopathologically confirmed diagnosis of breast cancer
* Aware of their diagnosis
* Able to read and complete the questionnaire
* Scheduled to undergo a standard chemotherapy regimen
Exclusion Criteria:
* History of severe psychiatric disorders (e.g., schizophrenia or bipolar disorder)
* Another prior cancer diagnosis
* Evidence of distant metastasis (stage IV disease)
* Severe comorbid conditions that could interfere with study participation or outcomes (e.g., severe cardiovascular disease or cognitive impairment)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This study is described as observational and longitudinal — meaning it tracks participants over time without giving a treatment — so would joining it affect my current breast cancer care plan in any way?
2The trial is measuring how financial stress, called 'financial toxicity,' affects quality of life in breast cancer survivors — given my own financial situation and the costs I'm already facing with treatment, is this the kind of research my doctor thinks could be meaningful for patients like me?
3Since this study isn't recruiting yet, how would I get notified when it opens, and is there a realistic window where I would still be considered a 'survivor' in the way this study defines it by the time enrollment begins?
4This study focuses on psychological resources alongside financial and quality-of-life measures — would participating require me to complete surveys or interviews about sensitive topics like stress or finances, and how much time commitment would that realistically involve?
5Are there other support programs or resources — like financial counseling or survivorship clinics — that my care team could connect me with now, rather than waiting to see if this study opens and if I might be eligible?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Quality of life
Timeframe: Baseline (T1, prior to first chemotherapy cycle), 2 months (T2, mid-treatment), and at 4 months (T3, completion of chemotherapy)