Perioperative Myocardial Injury in Patients Undergoing Coronary Artery Bypass Grafting: A Prospec… (NCT07650487) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Perioperative Myocardial Injury in Patients Undergoing Coronary Artery Bypass Grafting: A Prospective Clinical Study
China150 participantsStarted 2026-07-01
Plain-language summary
Perioperative myocardial injury (PMI) following coronary artery bypass grafting (CABG) is associated with postoperative morbidity, mortality, and long-term outcomes. High-sensitivity troponin assays and cardiac MRI offer reliable diagnostic tools for PMI, but evidence regarding optimal diagnostic thresholds and perioperative imaging strategy is limited. This prospective clinical study aims to determine the incidence of perioperative myocardial injury using multimodal assessments including high-sensitivity troponin, electrocardiogram, echocardiography, cardiac MRI, and perioperative cardiovascular events.
Who can participate
Age range
21 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Age ≥ 21 years
. Undergoing CABG for unstable angina
. Able to provide written informed consent
. No major cardiovascular event in the prior 6 months
Exclusion criteria
. Significant hepatic, renal, or other major organ dysfunction
. Pregnancy or breastfeeding
. Withdrawal during the study
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Since this trial is focused on measuring how often perioperative myocardial injury happens during coronary artery bypass grafting surgery, would participating mean any changes to how my surgery or post-operative monitoring would actually be managed, or is this purely an observational study where my care stays the same?
2This trial isn't recruiting yet — given that timeline uncertainty, would it make more sense for me to move forward with standard CABG surgery now rather than waiting to see if I might be eligible to participate?
3What does 'perioperative myocardial injury' actually mean in the context of bypass surgery, and how often does my care team see it happen in patients like me — is it something I should already be asking about regardless of this trial?
4Since this study is listed as Phase NA, which suggests it's observational rather than testing a new treatment, what benefit would I personally get from being enrolled, and would any data collected about my heart during surgery be shared back with me or my care team?
5Are there other active trials or newer surgical techniques for coronary artery disease that I should be asking about alongside this one, especially since this study hasn't started enrolling yet?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Incidence of Perioperative Myocardial Injury (PMI)