Lacrifill for Ocular Surface Optimization in Cataract Surgery (NCT07648095) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Lacrifill for Ocular Surface Optimization in Cataract Surgery
United States65 participantsStarted 2026-07-15
Plain-language summary
This is a single-site observational study designed to evaluate the efficacy of Lacrifill™ canalicular filler in optimizing ocular surface parameters and biometric precision in prospective cataract surgery patients with dry eye disease (DED).
Who can participate
Age range
40 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age \>= 40 years
* Diagnosed dry eye (OSDI \>= 13, TBUT \< 10 sec, or Oxford staining \>= Grade 2)
* No recent ocular surgeries (\<6 months)
* No significant changes in DED regimen within last 1 month
Exclusion Criteria:
* Previous punctal plugs or canalicular cautery
* Active ocular inflammation or corneal pathology unrelated to DED
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is studying whether a product called Lacrifill can improve the accuracy of cataract surgery measurements — can you explain what 'mean absolute error' means in this context and why reducing it might matter for my outcome?
2Since this trial hasn't started recruiting yet, how does that affect my options right now — should I proceed with standard cataract surgery, or is it worth waiting to see if I might be considered for this study?
3Lacrifill appears to be used to optimize the eye's surface before surgery measurements are taken — can you explain what ocular surface problems might be affecting my measurements, and whether this is something that already concerns you in my case?
4This trial is listed as Phase NA, which I understand may mean it's evaluating a device or procedure rather than a drug — what does that mean for what is and isn't yet known about the safety and effectiveness of using Lacrifill this way?
5If I were eventually considered for a trial like this, what would participation actually involve beyond my normal cataract surgery steps, and how might it affect my recovery timeline or follow-up visits?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.