Microvasculature Ultrasound Super-resolution in Transplant Delayed Graft Function (NCT07645599) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Microvasculature Ultrasound Super-resolution in Transplant Delayed Graft Function
United States40 participantsStarted 2026-06-01
Plain-language summary
This pilot study is testing a new ultrasound imaging method called Super-Resolution Ultrasound (SRU) to look at blood flow and tiny blood vessels in transplanted kidneys in very detailed images after kidney transplant surgery. The goal is to see whether changes in the kidney's small blood vessels can help predict how well the transplanted kidney will work early after transplant, including whether delayed graft function may occur.
Investigators hope this technique can become a safe, noninvasive way to evaluate transplanted kidneys without needing as many invasive biopsies. It may also help doctors better assess donor kidneys at higher-risk of suboptimal functioning.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. We will enroll patients ≥18 years of age
. Patients who received a kidney transplant 2a. Patients requiring dialysis in the first 14 days after transplant 2b. Patients with working allografts not requiring dialysis (control group)
. We will enroll patients at least 18 years of age or older
. Patients who received a kidney transplant 2a. Patients who received kidney transplants from low KDPI kidneys (KDPI \< 35) 2b. Patients who received kidney transplants from high KDPI kidneys (KDPI \> 75)
Exclusion criteria
. BMI \> 40
. Inability to provide informed consent
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial uses ultrasound super-resolution imaging to look at tiny blood vessels in a transplanted kidney — how is this different from the standard imaging my transplant team would already be doing, and would it give them any extra information about how my kidney is functioning?
2Since this study is listed as 'not yet recruiting,' do you know when it's expected to open, and would it make sense to revisit this option once enrollment begins rather than waiting on other decisions now?
3The trial is focused on delayed graft function after a kidney transplant — is that something my care team thinks I'm at higher risk for, and how would being in this study actually change how that's monitored or managed?
4Because this is a Phase NA study that seems to be measuring kidney vascularity rather than testing a new drug or treatment, what would participating actually involve for me in terms of extra procedures, visits, or time commitments around my transplant?
5Are there standard imaging or monitoring approaches already being used for transplant patients at this stage that would give us similar insights, or is this ultrasound technique something that isn't yet available outside of a research setting?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.