Frequency Rhythmic Electrical Modulated Stimulation Effect in Peripheral Neuropathy Patients Seve… (NCT07645482) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Frequency Rhythmic Electrical Modulated Stimulation Effect in Peripheral Neuropathy Patients Severity of Cases and Qol.
Egypt40 participantsStarted 2026-07
Plain-language summary
It's estimated that 50% of diabetic patients will have peripheral neuropathy as a complication within 3 years of the diabetes incidence \[14\], the goal of the study is to investigate this problem through the following objectives:
1. To measure the effect of using FREMS therapy in diabetic neuropathy in interventional group on the blood perfusion, neuropathy severity and quality of life after 10 sessions compared to baseline.
2. To measure the effect of using standard of care in diabetic neuropathy in control group on the blood perfusion, neuropathy severity and quality of life after 10 sessions compared to baseline.
3. To compare the results between both interventional and control group.
Who can participate
Age range
40 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* patients diagnosed with DM
* patients age group above 40 years old.
* patient diagnosed with peripheral neuropathy with symptoms lasts more than 3 months.
* patients lower limb ischemia in duplex affected APSV.
Exclusion Criteria:
* patients with implant peacemakers, defibrillator, or neurostimulator.
* pregnancy.
* any severe disease prevent compliance to study procedures.
* patients with disabilities prevent their commitment to sessions.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial uses something called Frequency Rhythmic Electrical Modulated Stimulation — can you explain how this type of electrical stimulation is supposed to work for diabetic peripheral neuropathy, and whether there's existing evidence suggesting it might help?
2Since this trial is listed as 'not yet recruiting,' how long might it be before it actually starts enrolling patients, and is there a reason to wait for it rather than starting an established treatment now?
3The trial is measuring both neuropathy severity and blood perfusion — does that mean the treatment is trying to improve circulation as well as nerve symptoms, and how would we track whether either of those things is actually changing in me?
4This trial doesn't have a numbered phase listed, which I understand can mean it's more of a feasibility or pilot study — does that affect how much we'd know about its safety and effectiveness compared to a more advanced trial?
5Are there standard treatments for diabetic peripheral neuropathy — like medications or physical therapy — that I should consider trying first, and how would starting one of those affect whether I might be eligible for this trial later?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Neuropathy severity
Timeframe: From enrollment to the end of treatment at 10:14 days
2
blood perfusion.
Timeframe: From enrollment to the end of treatment at 10:14days.