Maxillary Canine Retraction Using Stainless Steel and Titanium-molybdenum Alloy Wires in TAD-supp… (NCT07645417) | Clinical Trial Compass
By InvitationNot Applicable
Maxillary Canine Retraction Using Stainless Steel and Titanium-molybdenum Alloy Wires in TAD-supported Segmental Mechanics
Bangladesh16 participantsStarted 2025-07-01
Plain-language summary
The goal of this randomized clinical study is to compare the effectiveness of stainless steel (SS) and titanium-molybdenum alloy (TMA) wires for maxillary canine retraction using TAD-supported segmental mechanics. The main question it aims to answer is:
Which wire material, stainless steel or titanium-molybdenum alloy, provides better outcomes in maxillary canine retraction when used with TAD-supported segmental mechanics? Researchers will compare SS reverse-closing loops with TMA reverse-closing loops to evaluate differences in the rate of canine retraction and canine angulation changes during orthodontic space closure.
Participants will:
* Receive mini-implants/TADs on both sides of the maxillary arch.
* Receive a stainless steel reverse-closing loop on one side and a TMA reverse-closing loop on the contralateral side.
* Receive the same standardized force of 150 g on both sides.
* Visit the clinic every 4 weeks for a total duration of 4 months.
* Undergo OPG radiographs before retraction and after the 4-month study period to assess canine angulation.
Who can participate
Age range
15 Months – 35 Months
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Participants aged 15 to 35 years.
* Both male and female participants.
* Patients with all permanent teeth present, excluding third molars.
* Patients requiring extraction of both maxillary first premolars
* Patients with Class I or Class II molar relationship requiring maximum anchorage.
* Patients already undergoing fixed orthodontic treatment with a 0.018-inch Roth preadjusted appliance system.
* Maxillary canines aligned, symmetrical, and upright before the study.
* Patients in the leveling and alignment stage before canine retraction.
Exclusion Criteria:
* Missing or absent upper premolars.
* Previous orthodontic, orthognathic or reconstructive treatment.
* Systemic disease contraindicating dental implant placement.
* Use of systemic drugs or presence of systemic illness.
* Compromised periodontal condition.
* Use of anti-inflammatory therapy.
* Smokers.
* Pregnant female participants.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Comparison of the rate of maxillary canine retraction using stainless steel and TMA reverse-closing loops in TAD-supported segmental mechanics over 4 months.