Safety of Opportunistic Salpingectomy During Elective Laparoscopic Cholecystectomy. (NCT07642791) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Safety of Opportunistic Salpingectomy During Elective Laparoscopic Cholecystectomy.
Switzerland300 participantsStarted 2026-04-15
Plain-language summary
The knowledge, coupled with epidemiological studies demonstrating lower ovarian cancer rates in women with a history of tubal sterilization has led to recommendations for opportunistic salpingectomy at the time of benign gynecological surgery. However, this recommendation was not explored in the setting of non-gynecological surgeries, of most if the surgery performed not in pelvis.
This study aims to evaluate the safety of performing opportunistic salpingectomy at the time of elective laparoscopic cholecystectomy in women aged 45 years or older. Of note, the only available prospective study from Austria evaluated feasibility of combined operation. By assessing complication rates and other perioperative outcomes, the study seeks to determine if this combined approach is a safe for opportunistic ovarian cancer prevention. Ultimately, this research may inform surgical practice and potentially reduce the incidence of ovarian cancer in this population.
Who can participate
Age range
45 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Women aged 45 years or older.
* No known history of ovarian or fallopian tube cancer.
* Completed family planning.
* Scheduled to undergo elective laparoscopic cholecystectomy for benign gallbladder disease.
* Able to provide informed consent.
* Willing to comply with study procedures and follow-up assessments.
Exclusion Criteria:
* Previous abdominal Surgery or any inflammatory bowel disease.
* Current pregnancy or breastfeeding (verbally asked).
* Contraindications to laparoscopic surgery (e.g., severe cardiopulmonary disease, extensive prior abdominal surgery).
* Any medical condition that, in the opinion of the investigator, would preclude safe participation in the study or interfere with follow-up.
* Participation in another clinical trial that may confound the results of this study.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is combining a salpingectomy — removal of the fallopian tubes — with a routine gallbladder removal surgery, so could you explain why removing the fallopian tubes at the same time might reduce my future risk of ovarian cancer, and whether that potential benefit applies to my specific situation?
2Since this trial is listed as 'active, not recruiting,' does that mean the study is already enrolling patients or has closed to new participants, and are there similar studies I could still join if this approach interests me?
3The trial is measuring postoperative complications using something called the Comprehensive Complication Index — what kinds of complications are being tracked, and does adding a salpingectomy to my cholecystectomy meaningfully increase my surgical risk?
4This trial has no assigned phase, which often means it's focused on safety and feasibility rather than proving a benefit — given that, would you say the evidence is strong enough yet to recommend this combined approach, or would it be safer for me to just have the standard gallbladder surgery on its own?
5If I were a candidate for this kind of combined procedure, how would it affect my recovery time, hospital stay, or anesthesia exposure compared to having the cholecystectomy alone?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Postoperative complications assesed with Comprehensive complication index.