Nature as Medicine for the Healing Brain: Utilization of a Nature-based Exposure Intervention for… (NCT07642739) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Nature as Medicine for the Healing Brain: Utilization of a Nature-based Exposure Intervention for Decreasing Concussion Recovery Timeline and Symptom Load
United States24 participantsStarted 2026-07-01
Plain-language summary
The overall goal of this research is to provide pilot data that informs and drives a larger scale research project, incorporating multiple contemporary measurement modalities, to understand the utility and pathological mechanisms by which exposure to nature-based settings may aid in recovery time and symptom relief of individuals suffering from concussion, and decrease their risk of developing Persistent Post-Concussion Syndrome (PPCS).
We hypothesize that successful adherence to a nature-based exposure therapy intervention program will decrease recovery time and severity of symptom trajectory of concussion, as measured through multimodal assessments of brain structural and functional integrity.
Who can participate
Age range
14 Years – 35 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Require that any participant is 14-35 years old
. Required that any participant under 18 years old can be accompanied by a parent or legal guardian for the duration of the study
. Required that participants be English speakers
. Required that persons be able to provide consent for themselves
. Required that the participant must have suffered a clinically diagnoses concussion 5 days or less prior to the first study visit
. Concussion must have been diagnosed by a licensed clinical medicine professional.
. No additional professional treatment modalities outside of normal clinical concussion recovery recommendations may have been received prior to study participation. These include participation in a separate concussion rehabilitation study, cognitive behavioral therapies, vestibule-ocular therapies (balance), in-patient physical therapy, consumption of stimulant medication, and chiropractic manipulation.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is testing whether spending time in nature can help people recover faster from a concussion — is that something that might fit with whatever treatment plan you're already considering for me?
2Since this study isn't recruiting yet, how would we know when it opens and whether it would still be relevant to my recovery timeline, given that concussion recovery often happens in the weeks right after injury?
3The trial is measuring concussion symptom scales as its main outcome — what symptoms would they likely be tracking, and how do those compare to the symptoms I'm currently experiencing?
4This study is listed as Phase NA, which often means it's a behavioral or non-drug intervention rather than a medication trial — does that change the risk profile in a way that makes it more or less appropriate for someone in my situation?
5Are there standard concussion recovery approaches you'd recommend I try first, and if so, would pursuing those make me ineligible for a nature-based study like this one down the road?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Concussion Symptoms Scales
Timeframe: Daily, for the duration of the 28 day study
. Injury must have been diagnosed as a concussion or mild-traumatic brain injury. Participant must not have been diagnosed with of severe traumatic brain injury, hematoma, fractured skull or facial bones, or comatose.
Exclusion criteria
. Exclude persons under 14 years old or over 35 years old
. Exclude persons taking anti-inflammatory drugs (both prescription and OTC), or those who will have taken them within 24 hours prior to Visit 1
. Exclude smokers and former smokers, as defined by CDC. (Anyone who smokes daily or who has smoked at least 100 cigarettes in their lifetime)
. Those with presence of an active infection (including a dental infection)
. Exclude persons who have consumed alcohol within 48 hours prior to study participation, participants will be asked this by one of the study members through the exclusion criteria screening form when they first contact the study