UCLA Magnesium Formulation Athlete Study (NCT07640685) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
UCLA Magnesium Formulation Athlete Study
United States150 participantsStarted 2026-07
Plain-language summary
This randomized, double-blind, placebo-controlled trial will compare magnesium glycinate, magnesium L-threonate, and placebo in UCLA varsity athletes. Participants will complete a baseline monitoring period followed by 4 weeks of blinded nightly supplementation. WHOOP or study-approved wearable data will be used to evaluate sleep efficiency, total sleep time, sleep consistency, heart rate variability, resting heart rate, and recovery metrics. Baseline and final testing will assess selected reaction and physical performance outcomes. The primary outcome is change in WHOOP-derived sleep efficiency from baseline week to final treatment week.
Who can participate
Age range
18 Years – 35 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 18 to 35 years.
* Current UCLA varsity athlete.
* Actively training or competing during the study period.
* Willing to wear WHOOP or a study-approved wearable device continuously during baseline and treatment periods if wearable data are used.
* Willing to take assigned study capsules nightly for 28 days.
* Willing to complete brief daily REDCap surveys and weekly adherence/safety check-ins.
* Able to provide informed consent and comply with study procedures.
Exclusion Criteria:
* Current magnesium supplementation without completion of an appropriate washout before baseline.
* Current investigational drug or investigational supplement use.
* Current use of prescription or over-the-counter sleep medications unless reviewed and permitted by the study clinician.
* Diagnosed sleep disorder that, in the investigator's judgment, would confound outcomes or increase risk.
* Significant kidney disease or another medical condition that may increase risk with magnesium supplementation.
* Known intolerance or allergy to magnesium glycinate, magnesium L-threonate, placebo, or inactive study ingredients.
* Use of medications with clinically relevant magnesium interactions unless reviewed and permitted by the study clinician.
* Any other condition that, in the investigator's judgment, would make participation unsafe, compromise voluntary consent, or prevent valid outcome assessment.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in WHOOP-derived sleep efficiency percentage from baseline week to final treatment week
Timeframe: Baseline week to final treatment week, approximately 5 weeks total including baseline monitoring