Clinical Application Value of Deep Learning-Based "Opportunistic Screening" for Malignant Tumors … (NCT07639567) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Clinical Application Value of Deep Learning-Based "Opportunistic Screening" for Malignant Tumors on Routine Non-Contrast Chest-Abdomen-Pelvis CT
China100,000 participantsStarted 2026-07
Plain-language summary
This study aims to develop and validate a deep learning-based opportunistic multi-cancer screening system using routine non-contrast chest-abdomen-pelvis CT examinations, including CHANCE-Breast, CHANCE-Liver, CHANCE-Kidney, and CHANCE-Bladder, for the early detection of breast, liver, kidney, and bladder cancers. In addition, the study will assess a human-AI collaborative framework to determine its potential for improving cancer detection and reducing missed diagnoses in clinical practice.
Who can participate
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Patients with a confirmed diagnosis of the target malignancy who received treatment at our institution;
. Diagnostic-quality CT images without substantial metal or motion artifacts and with complete anatomical coverage of the target organ (breast, liver, kidney, or bladder);
. Availability of complete pre-treatment non-contrast CT imaging data.
Exclusion criteria
. Non-diagnostic image quality;
. Absence of a definitive reference-standard diagnosis;
. Incomplete clinical or imaging data.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.