Percutaneous Neurostimulation in Knee Osteoarthritis (NCT07637682) | Clinical Trial Compass
RecruitingNot Applicable
Percutaneous Neurostimulation in Knee Osteoarthritis
Egypt100 participantsStarted 2026-06-02
Plain-language summary
Peripheral nerve stimulation (PNS) is a drug-free pain management procedure that uses electrical impulses to target specific nerves and block pain signals. PNS helps decrease perception of pain, providing real answers to patients dealing with chronic knee pain. The case study discussed in this presentation is of the use of PNS targeting the superior lateral genicular nerve and the saphenous nerve for a patient with moderate to severe knee pain from osteoarthritis
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. adults between the ages of 30 and 70 years with a clinical diagnosis of moderate to severe knee OA who suffered knee pain.
. Patients who cannot afford intra-articular injections or radiofrequency ablation (RFA).
. patients who had failed 2 different oral pain medications and 6 weeks of physical therapy.
Exclusion criteria
. Patients with OA show improvement in pain after physiotherapy.
. patients evaluated by an orthopaedic surgeon and deemed to be surgical candidates due to knee pathologies other than OA.
. pregnant patients.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is measuring pain using a visual analogue scale — can you help me understand how meaningful that kind of change would need to be for it to actually improve my day-to-day life with knee osteoarthritis?
2Since this trial is listed as 'Phase NA,' which often means it's a device or procedure study rather than a drug trial, can you explain what that means for how much safety and effectiveness data already exists for this type of percutaneous neurostimulation in knee OA?
3How does this percutaneous neurostimulation approach compare to treatments I might already be eligible for, like physical therapy, corticosteroid injections, or other pain management options — would it make sense to try those first?
4What would the procedure actually involve in terms of how often I'd need to come in, how long sessions take, and whether there's any recovery time — and is that realistic given my current schedule and mobility?
5Are there specific things about my health history or the current severity of my knee osteoarthritis that would make this trial a poor fit, or that my care team should weigh carefully before I consider asking for a referral?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in visual analogue scale after intervention.