Effect of Medication Adherence-Based Digital Intervention on Fatigue Severity, Weight, and Thyroi… (NCT07636681) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Effect of Medication Adherence-Based Digital Intervention on Fatigue Severity, Weight, and Thyroid Hormone Regulation
Iraq80 participantsStarted 2026-06-01
Plain-language summary
1. To evaluate the effect of a medication adherence-based digital intervention on fatigue severity in patients with hypothyroidism.
2. To assess the effect of a medication adherence-based digital intervention on weight in patients with hypothyroidism.
3. To investigate the effect of a medication adherence-based digital intervention on thyroid hormone regulation in patients with hypothyroidism.
Who can participate
Age range
18 Years – 60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults (≥18 years) with primary hypothyroidism.
* On stable levothyroxine therapy for at least 3 months.
* Able to read, understand study instructions
* capable of using basic mobile applications
* poor medication adherence, clinically significant fatigue, documented weight fluctuations and abnormal thyroid hormone
Exclusion Criteria:
* Secondary hypothyroidism or recent thyroidectomy/radioactive iodine therapy.
* Pregnancy or breastfeeding woman.
* Severe psychiatric disorders or cognitive impairment
* significant visual or hearing deficits
* Serious comorbidities affecting medication adherence (e.g., chronic disease, renal, or hepatic disease).
* take dietary supplements or medications that interfere with levothyroxine absorption.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Fatigue Severity Score
Timeframe: Baseline and 3 months after intervention
2
Change in Body Weight
Timeframe: Baseline and 3 months after intervention.
3
Change in Thyroid Hormone Levels
Timeframe: Baseline and 3 months after intervention.