PLEASURE (Pleasing Lovers, Efficacy, Arousal, Satisfaction, and Uptake Research on Eroxon) (NCT07636161) | Clinical Trial Compass
Not Yet RecruitingPhase 4
PLEASURE (Pleasing Lovers, Efficacy, Arousal, Satisfaction, and Uptake Research on Eroxon)
United States30 participantsStarted 2026-09
Plain-language summary
The purpose of this research study is to look at whether Eroxon® gel when used together with tadalafil, may help improve erectile function in men ages 18 to 40 who have type 2 diabetes.
Who can participate
Age range
18 Years – 40 Years
Sex
MALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Male sex at birth
* Age 18-40 years
* Diagnosis of type 2 diabetes mellitus
* Diagnosis of erectile dysfunction
* Currently prescribed tadalafil
* Have a sexual partner willing to complete a survey
* Ability to provide informed consent
Exclusion Criteria:
* Type 1 diabetes mellitus
* Severe psychiatric illness that would impair participation
* Use of nitrates or contraindications to sexual activity
* Known allergy to Eroxon® gel components
* Participation in another interventional sexual health study
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is still listed as 'not yet recruiting' — do you know when it's expected to open for enrollment, and should I be thinking about other options in the meantime?
2Since this is a Phase 4 trial testing Eroxon, which means the drug is already approved, does that change the risk profile compared to earlier-phase studies, and is this treatment something I could potentially access outside of a trial right now?
3Given that my Type 2 diabetes is likely a contributing factor to my erectile dysfunction, how does this trial's focus on T2DM patients specifically affect whether it might be a better fit for me than a more general treatment approach?
4The trial is measuring changes in erectile functioning as its main outcome — how is that typically assessed, and are there any demands like frequent clinic visits or questionnaires that I should factor into my daily life before considering this?
5Are there standard treatments for diabetes-related erectile dysfunction that I should try first, or would my situation make it worth waiting to see if I qualify for this trial once it opens?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.