Evaluation of the Migraceutics® Phase-Specific Dietary Supplement Regimen on Quality of Life, Wor… (NCT07634146) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Evaluation of the Migraceutics® Phase-Specific Dietary Supplement Regimen on Quality of Life, Work Productivity, and Biomarkers in Adult Migraineurs: The Migraceutics® START Study
United States920 participantsStarted 2026-07-08
Plain-language summary
The purpose of this study is to evaluate the impact of the Migraceutics® phase-specific dietary supplement regimen on quality of life, work productivity, and biomarkers in adult migraineurs.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Self-reported history of migraine, based on the International Headache Society (IHS) International Classification of Headache Disorders, 3rd edition (ICHD-3) diagnostic criteria for migraine.
* Being able to take oral supplements.
* Agreeing to maintain their regular lifestyle.
* Access to internet and telephone.
Exclusion Criteria:
* Pregnancy or lactation.
* Presence of any active medical condition or diagnosis other than episodic migraine, including liver or kidney disease or condition.
* Use of overlapping supplements or interacting medications.
* Known allergies to study ingredients.
* Daily use of alcohol, tobacco, or recreational drugs.
* Participation in any other clinical or interventional study within 30 days prior to baseline or concurrently.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is testing a dietary supplement regimen rather than a prescription drug — given that it's labeled 'Phase NA,' what does that mean for how much safety and effectiveness data already exists compared to a standard pharmaceutical migraine treatment?
2The study is specifically looking at something called a 'phase-specific' supplement regimen, which seems to mean different supplements are taken at different points in the migraine cycle — does that approach make sense for my particular migraine pattern, and is it something worth discussing before I consider joining?
3Since this trial isn't recruiting yet, what current treatment options should I be pursuing in the meantime, and would starting a new preventive or acute migraine therapy now affect my eligibility if I wanted to join later?
4If I have menstrual migraines specifically, which this study seems to address, are there already evidence-based treatments you'd recommend I try first before considering an unapproved supplement regimen in a study?
5The trial is measuring changes in quality of life and work productivity — how would we track whether my migraines are actually improving during the study, and would I still have access to my usual rescue medications if I enrolled?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Changes from baseline in migraine-related quality of life