THE EFFECT OF AEROBIC AND RESISTANCE TRAINING ON THE IMMUNE SYSTEM (NCT07632911) | Clinical Trial Compass
By InvitationNot Applicable
THE EFFECT OF AEROBIC AND RESISTANCE TRAINING ON THE IMMUNE SYSTEM
Turkey (Türkiye)36 participantsStarted 2025-01-02
Plain-language summary
Six-week exercise interventions in sedentary young women demonstrated that aerobic exercise and resistance exercise differentially optimize inflammatory and immune responses through their effects on osteocalcin and IgM, and IgA, respectively. These distinct effects of exercise modality on immune biomarkers can be utilized to design personalized exercise programs.
Who can participate
Age range
18 Years – 35 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* University students aged 18-30
* Individuals who have engaged in recreational exercise at least two days a week for the past three months
* Those with low or no smoking or alcohol consumption who volunteer to participate in the study.
Exclusion Criteria:
* Individuals who have had an infection or chronic illness in the last 6 months,
* Those with a history of autoimmune disease,
* Metabolic syndrome, or cardiovascular disease,
* Those who have used antibiotics or anti-inflammatory drugs in the last 3 months,
* Those who have suffered a serious injury during exercise or are unable to continue are not eligible.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in C-Reactive Protein (CRP) Levels
Timeframe: Baseline (Week 0) and Post-intervention (Week 6)
2
Change in Interleukin-6 (IL-6) Levels
Timeframe: Baseline (Week 0) and Post-intervention (Week 6)
3
Change in Tumor Necrosis Factor-Alpha (TNF-α) Levels
Timeframe: Baseline (Week 0) and Post-intervention (Week 6)
4
Change in Salivary Immunoglobulin A (IgA) Levels
Timeframe: Baseline (Week 0) and Post-intervention (Week 6)
5
Change in Immunoglobulin M (IgM) Levels
Timeframe: Baseline (Week 0) and Post-intervention (Week 6)
6
Change in Immunoglobulin G (IgG) Levels
Timeframe: Baseline (Week 0) and Post-intervention (Week 6)
7
Change in Leukocyte (WBC) Count
Timeframe: Baseline (Week 0) and Post-intervention (Week 6)