A Pilot Study: Micro and NanoPlastics in Association With Crohn's Disease (NCT07630883) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
A Pilot Study: Micro and NanoPlastics in Association With Crohn's Disease
Hong Kong90 participantsStarted 2026-06-15
Plain-language summary
Micro and nanoplastics (MNPs) are environmental contaminants found in food and water. Recent evidence suggests these particles may be linked to intestinal inflammation and changes in gut bacteria, which are key features of Crohn's Disease (CD). This study aims to investigate if patients with Crohn's Disease have a reduced ability to clear these plastic particles and how this affects their immune system and intestinal health.
Who can participate
Age range
18 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Cases:
* Age 18-80 years
* Confirmed diagnosis of Crohn's disease (for cases)
* Ability to provide informed consent.
Control:
* Age 18-80 years old
* No history of major large bowel resection
* Ability to provide informed consent.
Exclusion Criteria:
Cases:
* Antibiotic/probiotic use within 4 weeks
* History of gastrointestinal malignancy
* Presence of stoma
* Currently Pregnant
* Advanced terminal medical illness, e.g. terminal malignancies; end staged renal failure and liver failure
Control:
* Currently Pregnant
* Advanced terminal medical illness, e.g. terminal malignancies; end staged renal failure and liver failure
* Inability in giving consent
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Micro- and nanoparticle abundance between subjects with Crohn's Disease and controls
Timeframe: Cross-sectional when the blood sample and the intestinal biopsy are collected.