3D Mapping Versus Conventional Ablation in AVNRT (NCT07630480) | Clinical Trial Compass
CompletedNot Applicable
3D Mapping Versus Conventional Ablation in AVNRT
Egypt80 participantsStarted 2023-12-30
Plain-language summary
This prospective randomized interventional study compared conventional fluoroscopy-guided slow pathway ablation versus three-dimensional electroanatomical mapping-guided ablation in patients with electrophysiologically confirmed typical atrioventricular nodal re-entrant tachycardia (AVNRT). A total of 108 patients were screened for eligibility, of whom 80 eligible patients were randomized in a 1:1 ratio to either conventional fluoroscopic ablation or 3D mapping-guided ablation. Following post-randomization dropouts, the final analysis included 38 patients in the conventional group and 36 patients in the 3D mapping group. The study evaluated fluoroscopy exposure, procedural efficacy, complete slow pathway elimination, procedural success, complications, and arrhythmia recurrence during follow-up.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Sustained symptomatic supraventricular tachycardia with surface ECG features highly suggestive of atrioventricular nodal re-entrant tachycardia (AVNRT).
* Electrophysiologically confirmed typical (slow-fast) AVNRT during the index electrophysiology study.
* Ability to provide written informed consent.
Exclusion Criteria:
* Coexisting arrhythmia requiring concurrent catheter ablation during the same procedure.
* Non-inducible AVNRT at the time of electrophysiological study.
* Antiarrhythmic drug use within 48 hours before the procedure or ongoing amiodarone therapy.
* Hemodynamic instability precluding safe catheter manipulation.
* Pregnancy.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial compared 3D mapping to conventional ablation specifically to measure radiation exposure — does the 3D mapping approach result in meaningfully less fluoroscopy time, and would that difference matter for my situation?
2Since this trial is already completed, has the data been published or shared yet, and can you tell me what the results showed about whether one technique was safer or more effective in terms of radiation dose?
3I have AVNRT and this trial was studying catheter ablation — is ablation the right path for me right now, or should I try medications first before considering any procedure?
4This trial wasn't assigned a formal phase, which I understand is common for procedure-based studies — but what does that mean for how confident you are in the safety and success rates of both the 3D mapping and conventional ablation approaches?
5If you were to perform a catheter ablation on me, which technique — 3D mapping or conventional fluoroscopy — would you use, and how does what this trial measured factor into that recommendation?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Total Fluoroscopy Radiation Dose During Catheter Ablation
Timeframe: At completion of the index ablation procedure
2
Total Fluoroscopy Exposure Time During Catheter Ablation
Timeframe: At completion of the index ablation procedure