Non-invasive Auricular Vagus Nerve Stimulation (taVNS) on Postural Control and Autonomic Response… (NCT07629687) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Non-invasive Auricular Vagus Nerve Stimulation (taVNS) on Postural Control and Autonomic Responses in Stroke
Pakistan22 participantsStarted 2026-05-20
Plain-language summary
This randomized controlled trial is conducted to determine the effects of transcutaneous auricular Vagus nerve stimulation (taVNS) on postural control in stroke patients (e.g., improvements in balance, mobility, and functional stability) and to evaluate the effects of taVNS on autonomic nervous system responses in stroke patients (e.g., changes in heart rate variability, blood pressure variability, skin conductance, and temperature).
Who can participate
Age range
18 Years – 70 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age between 18 to 70years who are diagnosed with ischemic brain injury, intracerebral hemorrhage shown by magnetic resonance imaging, or computed tomography.
* First occurrence of stroke characterized by a unilateral lesion, with an onset time (acute/ subacute) \< 6 months
* With balance impairment (BBS Score = 21-44);
* no or mild spasticity on the lower-limb assessed by Modified Ashworth Scale (MAS ≤ 2);
* sufficient cognition to follow the instructions provided by the therapists and the computer.
Exclusion Criteria:
* Individuals exhibiting unstable vital signs, consciousness disorders, or an inability to cooperate with examination and treatment procedures
* Those with a heart rate below 60 beats per minute, or with implantable devices such as pacemakers or cochlear implants.
* Other medical or psychological conditions affecting participation
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Berg Balance Scale (BBS)
Timeframe: 4 Weeks
2
Timed Up and Go Test (TUG)
Timeframe: 4 Weeks
3
Postural Assessment Scale for Stroke Patients (PASS)