Feasibility of Structured Resistance Training After Lower Extremity Fracture (NCT07629180) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Feasibility of Structured Resistance Training After Lower Extremity Fracture
Canada40 participantsStarted 2026-06-15
Plain-language summary
Adults recovering from surgically managed diaphyseal femur or tibia fractures often experience persistent weakness, pain, and functional limitations despite successful fracture healing. This prospective, non-randomized pilot study evaluates the feasibility and acceptability of a structured, supervised resistance training program initiated approximately 12 weeks after surgery, compared with usual postoperative care alone. The study will assess recruitment, adherence, retention, and protocol fidelity, and will collect exploratory patient-reported and physical function outcomes to inform the design of a future randomized controlled trial.
Who can participate
Age range
20 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults aged 20 to 65 years
* Diaphyseal femur or tibia fracture treated surgically with locked intramedullary nail fixation
* Cleared for full weight bearing with adequate fracture healing and no major complications
* Able to provide written informed consent in English without an interpreter
* Able to understand instructions and safely participate in supervised exercise
Exclusion Criteria:
* Bilateral fractures or open fractures; Polytrauma
* Cognitive impairment affecting participation or ability to provide informed consent
* Severe cardiac, respiratory, or neurological conditions that preclude exercise participation
* Chronic pain syndromes or recent opioid dependence
* Pre-existing severe lower limb disability
* Requires an interpreter for consent or cannot follow exercise instructions independently
* Unable to provide consent due to language barrier
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Recruitment rate (participants enrolled per month)
Timeframe: Up to 6 months
2
Adherence to supervised resistance training program (% of prescribed sessions completed)
Timeframe: Up to 6 months
3
Participant retention rate (% completing follow up assessments)
Timeframe: Up to 6 months
Trial details
NCT IDNCT07629180
SponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's