Effectiveness of Resistance Exercises Added to Aerobic and Balance Exercises in Parkinson's Disease (NCT07629063) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Effectiveness of Resistance Exercises Added to Aerobic and Balance Exercises in Parkinson's Disease
Turkey (Türkiye)34 participantsStarted 2025-09-01
Plain-language summary
The purpose of this study is to evaluate the effects of resistive exercises added to aerobic and balance exercises on quality of life, activities of daily living, cognitive functions, and sarcopenia parameters in patients diagnosed with early-stage PD. The main question it aims to answer is: In patients diagnosed with early-stage Parkinson's disease, do resistive exercises added to aerobic and balance exercises have an effect on quality of life, daily living activities, cognitive function, and sarcopenia parameters? If so, what is the nature of this effect? Patients will undergo an exercise program three days a week for eight weeks. Outcomes will be assessed at baseline, on the first day after the treatment and 4 weeks after the end of the treatment.
Who can participate
Age range
40 Years – 70 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults aged 40 to 70 years
* Patients diagnosed with Modified Hoehn-Yahr stage 1-3 Parkinson's disease
* Patients diagnosed with Parkinson's disease for more than 1 year
* Patients who can mobilize without an assistive device
Exclusion Criteria:
* Patients diagnosed with Parkinson Plus syndrome
* History of uncontrolled hypertension
* History of uncontrolled diabetes mellitus
* History of serebrovascular disease within the past 6 months
* History of miyocardial infarction within the past 6 months
* History of knee or hip artroplasty surgery
* History of severe cardiac arrythmia
* Presence of cardiac pacemaker
* Presence of severe dementia
* History of severe psychiatric disorders
* Patients who have on dialysis
* Presence of acute infection
* Pregnancy
* History of malignancy
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is testing resistance exercises added to aerobic and balance training for Parkinson's disease and sarcopenia — given my current muscle strength and balance situation, is this kind of combined exercise program something my care team would even recommend for me right now?
2The trial is measuring grip strength, chair stand performance, and gait speed as its main outcomes — are these things my doctor is already tracking for me, and would knowing my current scores help us understand whether this type of program might address my specific needs?
3Since the trial is no longer actively recruiting, I can't join it — but could my doctor point me toward a similar supervised resistance and aerobic exercise program that's available to me now, either through physical therapy or another study?
4This trial also involves people with sarcopenia, which is age-related muscle loss — has my doctor assessed whether I have sarcopenia on top of my Parkinson's, and should that affect the type of exercise program I pursue?
5How does adding resistance training to aerobic and balance exercises compare to what I'm already doing or what standard Parkinson's care recommends — is there a reason to prioritize one type of exercise over another for someone at my stage?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Grip strenght
Timeframe: Baseline (pre-treatment), Day 1 post-treatment, Week 4 post-treatment
2
Chair Stand Test
Timeframe: Baseline (pre-treatment), Day 1 post-treatment, Week 4 post-treatment
3
Gait Speed
Timeframe: Baseline (pre-treatment), Day 1 post-treatment, Week 4 post-treatment
Trial details
NCT IDNCT07629063
SponsorSisli Hamidiye Etfal Training and Research Hospital