RecruitingNot Applicable

Postoperative Cryocuff vs. Conventional Icepack in TKA - What is More Effective in Reducing Pain and Swelling?

Germany102 participantsStarted 2026-05-27

Plain-language summary

Topic/Disease Pattern Postoperative pain and swelling management after knee prosthesis implantation using cryotherapy Objective To determine possible differences in postoperative swelling and pain following primary total knee arthroplasty (TKA) under cryotherapy using cuff cooling versus conventional ice pack treatment. Study Plan Treatment of the cohort using cuff cooling and comparison with a control group receiving conventional treatment with ice packs. Study-Related Measures Pre- and postoperative examinations according to the examination and data collection plan Evaluation after completion of full recruitment

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Signed informed consent form (signed by the patient and the responsible study physician) * Primary total knee arthroplasty (TKA) Age ≥ 18 years * Willingness to document the NRS score and subjective feeling of tightness after 4 weeks Exclusion Criteria: * Obesity with BMI ≥ 40 * Lymphedema * Lymphatic drainage therapy * Revision total knee arthroplasty (TKA) surgeries * Primary unicondylar knee arthroplasty * Study physicians, relatives, employees, or other dependent persons

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

postoperative swelling

Timeframe: from enrollment to 4 weeks postop

postoperative pain

Timeframe: from enrollment to 4 weeks postop

Trial details

NCT IDNCT07627854

SponsorProf. Dr. med. Andreas Halder

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-10-01

Contact for this trial

Thomas Gerhards

+493305552273 thomas.gerhards@sana.de

View on ClinicalTrials.gov More Postoperative Swelling After TKA trials