Efficacy of Adjunctive Theravex Tissue Care® With Xenograft in Internal Sinus Lifting (NCT07627633) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Efficacy of Adjunctive Theravex Tissue Care® With Xenograft in Internal Sinus Lifting
Egypt16 participantsStarted 2026-10-01
Plain-language summary
The purpose of this clinical study is to evaluate the clinical and radiographic efficacy of Theravex Tissue Care Plus (Bone Bioactive Liquid) as an adjunct to a xenograft in crestal maxillary sinus elevation with simultaneous implant placement using the osseodensification technique. The study will enroll 16 partially edentulous patients who have inadequate posterior maxillary bone height. Participants will randomly undergo the sinus elevation and implant placement utilizing either a xenograft alone or a mixture of the xenograft and Theravex. The main question the study aims to answer is whether the adjunctive use of Theravex with a xenograft enhances vertical bone gain, bone density, and implant stability compared to using a xenograft alone.
Who can participate
Age range
21 Years – 50 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patient partially edentulous with maxillary posterior edentulous ridge after extraction of more than 4 months.
* Both genders will be selected males and females.
* Adult patients aged between 21 and 50 years of age.
* Good general health (American Society of Anesthesiology Physical Status I-II).
* Initial residual alveolar ridge height ranging between 4 to 6 mm according to preoperative CBCT.
* No previous surgery or radiation treatment on the maxillary sinus
Exclusion Criteria:
* Smokers
* Pregnant and lactating females.
* Poor oral hygiene (Full-Mouth Plaque Score (FMPS) \> 20%).
* Patients with occlusal or malalignment problems.
* Patients with parafunctional habits.
* Presence of acute or chronic sinus pathoses or sinus membrane perforation.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Implant Stability Quotient (ISQ)
Timeframe: Immediate post-operative and 3 months post-operative