Frailty in the Elderly Oncological and Oncohematological Patient.

Inclusion Criteria: Inclusion criteria for patients with solid tumors: * Cytological or histological diagnosis of lung cancer or gastrointestinal tract tumors (esophageal, gastric, intestinal, colorectal, pancreatic, and biliary tract cancers), mesothelioma. * Age ≥ 70 years * Patients deemed eligible, at the investigator's discretion, for first-line treatment including at least one chemotherapeutic agent * Previous treatments (e.g., adjuvant therapy) are allowed if completed at least one year prior to randomization * ECOG performance status 0, 1, or 2 * Written informed consent obtained Inclusion criteria for patients with hematologic malignancies: * Cytological or histological diagnosis of multiple myeloma or lymphoma * Age ≥ 70 years * Patients deemed eligible, at the investigator's discretion, for first-line systemic treatment * ECOG performance status 0, 1, 2, or 3 * Written informed consent obtained Exclusion Criteria: * Brain metastases (in solid tumors) * Symptomatic bone lesions (in solid tumors) * Cardiac disease classified as NYHA class III or IV * Current or prior prostate or breast cancer receiving hormonal therapy (GnRH agonists or antagonists, androgen inhibitors, estrogen inhibitors) * Acute leukemia * Patients with pacemakers or implantable cardioverter-defibrillators (ICD)