NeuroFinance Human Stress Trial During Financial and Informational Volatility (NCT07622589) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
NeuroFinance Human Stress Trial During Financial and Informational Volatility
United States2,500 participantsStarted 2026-07-15
Plain-language summary
The NeuroFinance Human Stress Trial (NFHST-2026-001) is a decentralized observational clinical study designed to evaluate how financial market volatility, economic uncertainty, digital media exposure, and information-driven stress environments affect human physiologic and behavioral health. Participants will undergo remote monitoring using wearable biosensors, cardiovascular telemetry devices, sleep tracking systems, heart rate variability monitoring, and behavioral analytics platforms. The study will use artificial intelligence and machine learning systems to analyze relationships between external financial and informational events and biologic stress responses, including autonomic nervous system activity, sleep disruption, cardiovascular strain, emotional resilience, and inflammatory signaling. The goal of the study is to develop predictive digital biomarkers and AI-assisted forecasting systems capable of identifying stress-related physiologic deterioration before clinical manifestation.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults age 18 years and older.
* Ability to provide informed consent.
* Willingness and ability to comply with study procedures and remote monitoring requirements.
* Access to a compatible smartphone, tablet, or internet-connected device for decentralized study participation.
* Willingness to utilize wearable physiologic monitoring technologies during the study period.
* Participants with varying degrees of financial market exposure, occupational stress exposure, or digital media exposure are eligible.
* Healthy volunteers and participants with self-reported stress-related symptoms may be enrolled.
* Ability to read and understand English-language consent and study materials.
Exclusion Criteria:
* Individuals unable or unwilling to provide informed consent.
* Individuals unable to comply with remote monitoring procedures or wearable device usage requirements.
* Active medical or psychiatric instability that, in the opinion of study investigators, may interfere with study participation or data integrity.
* Current incarceration or institutionalization limiting voluntary participation.
* Participation in another interventional clinical trial that may substantially interfere with physiologic monitoring outcomes.
* Any condition that would significantly impair safe study participation as determined by the study investigators.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is listed as 'not yet recruiting' — is it worth me keeping an eye on it for the future, or are there similar studies already enrolling that might be a better fit for my situation right now?
2The trial seems to focus on observing and measuring stress responses — like heart rate variability, sleep duration, and perceived stress scores — rather than testing a treatment, so does that mean there's no intervention being offered, and would participating actually change anything about how my stress or sleep problems are managed?
3Since this study is tracking things like heart rate variability and resting heart rate during financial stress exposure, would my doctor need to review my current heart health or any medications I take that affect heart rate before I could even consider something like this?
4Given that this trial covers a wide range of issues — including occupational stress, burnout, anxiety, and sleep disturbance — how would my doctor know which of my specific symptoms are the focus here, and whether this study's measurements are actually relevant to my personal health goals?
5If this is a purely observational study with no treatment phase, would my doctor recommend I pursue this alongside standard care for my stress or sleep issues, or is it better to focus on getting those addressed through existing options first?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Heart Rate Variability (HRV) During Financial Stress Exposure
Timeframe: Baseline through 24 Months
2
Change in Sleep Duration
Timeframe: Baseline through 24 Months
3
Change in Resting Heart Rate
Timeframe: Baseline through 24 Months
4
Change in Perceived Stress Scale-10 (PSS-10) Total Score