The Effect of Exercise on Cognitive Functions in Individuals With Systemic Lupus Erythematosus (NCT07622251) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
The Effect of Exercise on Cognitive Functions in Individuals With Systemic Lupus Erythematosus
Turkey (Türkiye)38 participantsStarted 2026-06-05
Plain-language summary
Study Objective:
To examine the effect of aerobic exercise on disease activity and cognitive functions in patients diagnosed with SLE. Study Goals:
1. To conduct comprehensive pre- and post-treatment (after 12 weeks) evaluations of SLE patients included in the study, and to determine their disease activity and cognitive levels.
2. To apply aerobic exercise to SLE patients for three months.
3. To analyze the effects of the aerobic exercise program on disease activity and cognitive functions.
Who can participate
Age range
25 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Having been diagnosed with SLE at least one year prior according to the American Rheumatology Association (ACR) diagnostic criteria
* Being between 25-65 years of age
* Not having received a neuropsychiatric diagnosis
* Having medication adjusted and being on stable medication for 3 months
* Not being involved in a regular exercise program
* Having a Mini Mental Test score lower than 26.
Exclusion Criteria:
* History of secondary rheumatic disease
* Presence of active acute or chronic infection,
* Body mass index (BMI) ≥ 30 kg/m2,
* Acute renal failure,
* Cardiac and pulmonary involvement,
* Presence of musculoskeletal and joint disorders that prevent exercise testing,
* Pregnancy
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is measuring cognitive function in SLE patients using the Mini Mental Test — does that match the kind of memory or thinking problems I've been experiencing, and is that test sensitive enough to capture what I'm going through?
2Since this trial hasn't started recruiting yet, how long might I realistically have to wait before I could even be considered, and is there anything I should be doing in the meantime to support my cognitive health?
3The trial is listed as 'Phase NA,' which often means it's a non-drug behavioral study — can you help me understand what the exercise program might actually involve, and whether my current lupus symptoms or flare history would make it safe for me to participate?
4Given that SLE can cause fatigue and joint pain, how would a structured exercise program be managed around my specific disease activity, and could pushing through an exercise protocol actually risk triggering a flare?
5Are there any standard-of-care options or already-completed studies on exercise and cognition in lupus that might benefit me now, rather than waiting for this trial to open?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.