Abdominal Midline Wound Closure: Small Tissue Bites Versus Large Tissue Bites (NCT07621926) | Clinical Trial Compass
CompletedNot Applicable
Abdominal Midline Wound Closure: Small Tissue Bites Versus Large Tissue Bites
Pakistan88 participantsStarted 2025-05-01
Plain-language summary
The goal of this clinical trial is to learn whether a small stitch technique works better than a large bite technique for closing midline abdominal surgery wounds in adults having midline laparotomy surgery.
The main questions it aims to answer are:
Does the small stitch technique lower the risk of surgical site infection? Does the small stitch technique lower the risk of wound dehiscence (reopening of the wound)? Researchers will compare the small stitch technique with the large bite technique to see if the small stitch technique leads to fewer wound complications after surgery.
Participants will:
Have their abdominal wound closed using either the small stitch or large bite technique during surgery Attend follow-up visits at 2 weeks and 1 month after surgery Be checked for wound complications, including infection and wound reopening In the small stitch technique, stitches are placed 5 millimeters from the wound edge and 5 millimeters apart. In the large bite technique, stitches are placed 10 millimeters apart.
Who can participate
Age range
18 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
. Age 18-80 years, either sex
* Midline laparotomy (elective or emergency)
* ASA class I-IV
Exclusion Criteria:
* Previous incisional hernia or midline incision
* Contaminated surgery
* ASA V-VI
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial compared small tissue bites versus large tissue bites for closing abdominal wounds — which technique did my surgical team use for my closure, and does the evidence from studies like this one influence their practice?
2Since this trial was measuring sheath dehiscence, which is when the abdominal wall layers separate after surgery, how would my doctor recognize that complication early, and what are my personal risk factors for it?
3This study has already been completed — does my doctor know whether the results have been published, and if so, did one stitching technique show a meaningful difference in wound separation rates that might be relevant to my care?
4Because this was a trial about surgical technique rather than a drug or device, does my doctor think the findings would apply to my specific type of abdominal surgery, given that different procedures may carry different closure challenges?
5Are there other steps my care team takes after abdominal surgery — like wound support, activity restrictions, or follow-up checks — that work alongside the closure technique to reduce the risk of the kind of wound breakdown this trial was studying?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.