Peritoneal Transport With a New Bicarbonate-based Peritoneal Dialysis Solution Compared to Conven… (NCT07621627) | Clinical Trial Compass
CompletedPhase 3
Peritoneal Transport With a New Bicarbonate-based Peritoneal Dialysis Solution Compared to Conventional Solution.
Sweden7 participantsStarted 1997-09-09
Plain-language summary
Cross-over study. Patients treated with peritoneal dialysis are investigated twice with a single 4h dwell study: once with Bicarbonate-Lactate solution as buffer (Physioneal TM) and once with conventional lactate PD solution (Dianeal TM). Radioidinated human serum albumin is used as a volume marker to assess ultrafiltration and frequent dialysis and blood sampling to assess peritneal transport of solutes and pH changes.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* patient treated with peritoneal dialysis in a clinically stable condition
Exclusion Criteria:
* none
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial has already been completed — would my doctor be able to share or access the results showing how the new bicarbonate-based solution compared to the standard one in terms of fluid removal (ultrafiltration)?
2Since this was a Phase 3 trial measuring net ultrafiltration, does that mean the new bicarbonate-based peritoneal dialysis solution is closer to being available as a standard treatment option, and could it be relevant for my care?
3How important is net ultrafiltration — the amount of fluid removed during peritoneal dialysis — for my specific situation, and would a difference in that measurement between the two solutions actually change my day-to-day health outcomes?
4Would my doctor consider the bicarbonate-based solution tested in this trial to be potentially gentler on the peritoneal membrane over the long term compared to the conventional solution I might currently be using or starting on?
5Before considering anything from this trial, are there already established standard peritoneal dialysis solutions my doctor would recommend first, and how would we decide if switching to a bicarbonate-based option might be worth discussing?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.