Comparison of ESWT and Single-Session 5% Dextrose Prolotherapy in Lateral Epicondylitis (NCT07620678) | Clinical Trial Compass
CompletedNot Applicable
Comparison of ESWT and Single-Session 5% Dextrose Prolotherapy in Lateral Epicondylitis
Turkey (Türkiye)96 participantsStarted 2023-10-01
Plain-language summary
Lateral epicondylitis is a common musculoskeletal disorder associated with pain and impaired upper extremity function. The aim of this study was to compare the effectiveness of extracorporeal shock wave therapy (ESWT) and single-session 5% dextrose prolotherapy (DPT) in patients with lateral epicondylitis and to evaluate the relative superiority of these treatment approaches during short- and mid-to-long-term follow-up. Ninety-six patients were allocated into three groups: conventional treatment alone, conventional treatment plus ESWT, and conventional treatment plus DPT. Pain, functional status, grip strength, and common extensor tendon thickness were evaluated during follow-up.
Who can participate
Age range
18 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults aged 18-75 years
* Clinical and ultrasonographic diagnosis of lateral epicondylitis
* Symptoms persisting for at least 3 months
* Visual Analog Scale (VAS) score ≥4
* Resistance to previous medical treatment
* Ability to comply with study procedures and complete questionnaires
Exclusion Criteria:
* Injection treatment for lateral epicondylitis within the previous 3 months
* History of trauma within the previous 3 months
* Cervical disc herniation
* Median or ulnar tunnel neuropathy
* Medial epicondylitis
* Anticoagulant therapy use
* Pregnancy or breastfeeding
* Psychiatric disorders or cognitive impairment interfering with questionnaire -completion
* Allergy to the treatment solution
* History of upper extremity surgery or fracture
* Rheumatoid arthritis
* Connective tissue diseases such as dermatomyositis
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
VAS Resisted Wrist Extension Pain
Timeframe: Baseline, 1 month, 3 months, and 6 months after treatment
2
VAS Gripping Pain
Timeframe: Baseline, 1 month, 3 months, and 6 months after treatment
3
VAS Resting Pain
Timeframe: Baseline, 1 month, 3 months, and 6 months after treatment
4
VAS Night Pain
Timeframe: Baseline, 1 month, 3 months, and 6 months after treatment
Trial details
NCT IDNCT07620678
SponsorGaziler Physical Medicine and Rehabilitation Education and Research Hospital