RecruitingNot Applicable

Machine Learning Model Based on Baroreflex Sensitivity for Predicting Post-Induction Hypotension in Elderly Patients

China500 participantsStarted 2026-06-01

Plain-language summary

The purpose of this study is to develop a high-performance machine learning model combining dynamic baroreflex sensitivity (BRS) metrics and multi-dimensional static clinical features to predict the risk of post-induction hypotension (PIH) in elderly patients undergoing elective non-cardiac surgery under general anesthesia.

Who can participate

Age range

65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Aged over 65 years; * Scheduled for elective non-cardiac surgery; * American Society of Anesthesiologists (ASA) physical status classification I-III; * Planned for general anesthesia with endotracheal intubation; * Patient and legal guardians are capable of understanding the study protocol and willing to provide written informed consent. Exclusion Criteria: * Severe peripheral vascular diseases; * Secondary hypertension; * Presence of physical tremors (e.g., Parkinson's disease) preventing stable recording; * Inability to accurately measure upper limb blood pressure; * Pre-existing cardiac arrhythmias (e.g., atrial fibrillation) that render BRS; * Psychiatric disorders or cognitive impairments hindering basic cooperation.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Incidence of Post-Induction Hypotension (PIH)

Timeframe: From immediately after anesthesia induction up to 20 minutes post-induction or before surgical incision.

Trial details

NCT IDNCT07618416

SponsorPeking Union Medical College Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-09-30

Contact for this trial

Quexuan Cui, Dr.

+8613520921711 Cuiqx_garfield@126.com

View on ClinicalTrials.gov More Post Induction Hypotension trials