A Study on the Efficacy of Sodium Propionate Combined With Anti-PD-1 Immunotherapy in Gastric Cancer (NCT07615907) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
A Study on the Efficacy of Sodium Propionate Combined With Anti-PD-1 Immunotherapy in Gastric Cancer
China20 participantsStarted 2026-05-30
Plain-language summary
Eligible patients were randomized into two groups: the sodium propionate group and the control group. In the control group, patients received placebo combined with anti-PD-1 therapy plus chemotherapy without additional sodium propionate intervention. In the sodium propionate group, on the basis of anti-PD-1 therapy combined with chemotherapy, patients were additionally administered oral sodium propionate capsules at a dose of 500 mg (1 capsule) twice weekly, with a total intervention duration of 12 weeks. The primary and secondary outcome indicators will be collected for subsequent analysis.
Who can participate
Age range
18 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Subjects voluntarily participated in the trial and signed the informed consent form;
* Aged ≥ 18 years and \< 80 years, regardless of gender;
* Stable vital signs;
* Patients with gastric adenocarcinoma confirmed by gastroscopic biopsy;
* Tumors judged as unresectable by attending physicians;
* Receiving anti-PD-1 therapy combined with chemotherapy as first-line treatment;
* No history of allergic diseases and non-allergic constitution;
* No history of drug abuse;
* Non-pregnant and non-lactating females (applicable to male subjects as well);
* No participation in any drug clinical trial (including investigational drugs of this trial) within 3 months prior to enrollment.
Exclusion Criteria:
* Failure to meet the inclusion criteria, or individuals deemed inappropriate for trial participation by investigators;
* Concurrent primary malignant tumors at other sites;
* Poor general condition, severe infection, respiratory insufficiency, or other conditions leading to inability to cooperate with the trial;
* Patients with mental disorders, consciousness disturbance, or poor treatment compliance;
* Suspected or confirmed history of drug abuse;
* Immunodeficiency, or long-term use of immunosuppressants and glucocorticoids;
* Pregnant or lactating women;
* Sponsors, investigators directly involved in this trial, and their immediate family members;
* Individuals unsuitable for enrollment for any reason as judged by the investigator.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.