Clinical Study to Collect and Analyze Dental Plaque and Oral Health Measures in a Population With… (NCT07614490) | Clinical Trial Compass
RecruitingPhase 4
Clinical Study to Collect and Analyze Dental Plaque and Oral Health Measures in a Population With High Plaque/Low Gingivitis and High Plaque/High Gingivitis
United States100 participantsStarted 2026-04-20
Plain-language summary
The objective of this clinical research study is to collect and analyze plaque and oral health measures in a population with high plaque/low gingivitis and high plaque/high gingivitis
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Male or female volunteers at least 18 years of age and in general good health.
* Willing and able to understand and sign the informed consent form.
* Must have a whole mouth mean TPI score ≥ 3.25
* N=40 must have moderate-severe gingivitis (Whole Mouth Mean MGI≥2.5 or percent bleeding sites based on EBI ≥20%) and N=40 must have mild gingivitis (Whole Mouth Mean MGI≤2.5 and percent bleeding sites based on EBI\<20%)
* Must have at least two areas in the mouth with high plaque/low inflammation and two areas with high plaque/high inflammation
* Be willing to conform to the study protocol and procedures.
* Minimum of 20 natural teeth with scorable facial and lingual surfaces
Exclusion Criteria:
* Medical condition which requires premedication prior to dental visits/procedure.
* Known history of allergy to personal care/consumer products or their ingredients, relevant to any ingredients in the test products as determined by the study examiner.
* Active disease of the hard oral tissues.
* Significant oral soft tissue pathology, excluding plaque-induced gingivitis.
* Subjects with fixed or removable orthodontic appliances or removable partial dentures.
* Dental prophylaxis within 30 days prior to study start.
* Use of antibiotics, antimicrobial drugs, anti-inflammatory drugs, or anticoagulant therapies within 30 days prior to study start.
* Use of chemotherapeutic oral care products within two weeks prior to study start.
* Participation in any other clinical …
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Relative abundance of Streptococcus and Porphyromonas