Not Yet RecruitingNot Applicable

This Study is Conducted to Evaluate the Clinical Performance of Indirect Overlay Restorations With Different Cavity Preparation Designs in Endodontically Treated Molars.

50 participantsStarted 2026-06-15

Plain-language summary

This study is conducted to evaluate the clinical performance of indirect overlay restorations with different cavity preparation designs in endodontically treated molars over two years.

Who can participate

Age range

20 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Patient Related Criteria: * Adult patients (age: 20-60 years) of both genders. * Healthy patients (not suffering of any systematic or chronic diseases). * Able to tolerate the necessary restorative procedures. * Willing to sign the informed ethical consent. * Accepts the follow-up period. Tooth Related Criteria: * Proper endodontically treated teeth. * First and second permanent molars. * Absence of any peri-apical lesions. * Absence of any periodontal disease involvement. * Large access cavities with one or two missing walls. * Patients with proper oral hygiene. * Presence of opposing tooth. Exclusion Criteria: * Patient related: * Patients younger than 20 or older than 60 years old. * Pregnant females. * Patients with any systemic or chronic diseases. * Patients not accepting the follow-up period. * Patients not willing to sign the informed ethical consent. * Patients with known allergies to latex and/or resinous material. Tooth related * Endodontically treated anterior, premolar and third molar teeth. * Hopelessly carious/destructed teeth necessitating extraction. * Mobile teeth, indicating periodontal disease or trauma. * External or internal resorption. * Poor endodontic treatment. * Periapical lesion present. * Cervical carious lesions involved.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Marginal adaptation (success rate)

Timeframe: T0: baseline T1: 6 months T2: 12 months T3: 18 months T4: 2 years

Trial details

NCT IDNCT07614451

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-06-15

Contact for this trial

Sara Ibrahim Fahmy, PhD

01006256086 sara.fahmy@dentistry.cu.edu.eg

View on ClinicalTrials.gov More Endodontically Treated Molar trials

Who can participate

Age range

20 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.