MacuTherm Performance Study in Patients With iAMD

Key Inclusion Criteria: * Male, female, or diverse * Age of 60 to 90 years old * Clinically confirmed intermediate AMD (iAMD, AREDS category 3) with the presence of: * At least 3 large drusen (diameter \> 125 μm) within the inner ring of 3mm diameter of the ETDRS Grid centered on the fovea (with or without reticular pseudodrusen (RPE)) * combined with at least 1 of the following other signs: * Incomplete RPE and outer retinal atrophy (i-RORA) outside central 1mm ring and/or * Hyperreflective foci (HRF) adjacent to drusen (within 3 mm) * Best corrected visual acuity between 65 and 87 letters * Clear optic media * Ability to communicate clearly and to understand and comply with the nature and requirements of the study * Ability to provide written informed consent in accordance with institutional, local and national regulatory guidelines * Willing to participate Exclusion Criteria: * Presence of late-stage AMD, neovascular (nAMD, active or fibrotic) or geographic atrophy (GA) * Maculopathies showing only pseudodrusen * Any systemic medication known to be toxic to the lens, retina or optic nerve * Any intraocular surgery within 6 months prior to study inclusion (except uncomplicated cataract surgery \> 3 months) * Any previous thermal laser treatment in the macula * History of vitrectomy, filter surgery, corneal transplantation or retinal detachment * Previous therapeutic radiotherapy in the eye region * Pregnant or breast-feeding patients * Participation in an i…