RIPB Versus EOIPB for Pain Control After Laparoscopic Cholecystectomy (NCT07607262) | Clinical Trial Compass
CompletedNot Applicable
RIPB Versus EOIPB for Pain Control After Laparoscopic Cholecystectomy
Turkey (Türkiye)60 participantsStarted 2026-04-25
Plain-language summary
This prospective observational study aims to compare the effects of bilateral ultrasound-guided recto-intercostal plane block(RIPB) and bilateral ultrasound-guided external oblique intercostal plane block(EOIPB) on postoperative analgesia in patients undergoing elective laparoscopic cholecystectomy under general anesthesia.
Both blocks are performed after anesthesia induction as part of routine preemptive multimodal analgesia practice. Patients who receive bilateral recto-intercostal plane block will be included in the RIPB group, and patients who receive bilateral external oblique intercostal plane block will be included in the EOIPB group.
The primary outcome is cumulative intravenous tramadol consumption via patient-controlled analgesia during the first 24 postoperative hours. Secondary outcomes include postoperative pain scores at rest and during activity, rescue analgesic requirement, postoperative nausea and vomiting, time to mobilization, length of hospital stay, quality of recovery assessed using the Quality of Recovery-15 questionnaire, and block-related complications.
Who can participate
Age range
18 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age between 18 and 75 years
* American Society of Anesthesiologists (ASA) physical status I-III
* Scheduled for elective laparoscopic cholecystectomy under general anesthesia
* Written informed consent obtained
Exclusion Criteria:
* Refusal to participate
* Inability to understand the study protocol or provide informed consent
* Known allergy to local anesthetics, tramadol, paracetamol, dexketoprofen, or other study drugs
* Chronic opioid or steroid use
* Psychiatric or cognitive disorder preventing reliable pain assessment
* Inability to use patient-controlled analgesia
* Pregnancy or breastfeeding
* Coagulopathy
* Infection at the block site
* Difficult or prolonged intubation requiring three or more attempts
* Conversion to open surgery
* Surgery lasting longer than 120 minutes
* Intraoperative or postoperative complications requiring deviation from the standard analgesia protocol
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Cumulative Postoperative Tramadol Consumption
Timeframe: Postoperative 24 hours
Trial details
NCT IDNCT07607262
SponsorSehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital